Incidence of rhegmatogenous retinal detachments after intravitreal antivascular endothelial factor injections

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dc.contributor.authorMeyer, Carsten H.
dc.contributor.authorMichels, Stephan
dc.contributor.authorRodrigues, Eduardo B. [UNIFESP]
dc.contributor.authorHager, Annette
dc.contributor.authorMennel, Stefan
dc.contributor.authorSchmidt, Joerg C.
dc.contributor.authorHelb, Hans-Martin
dc.contributor.authorFarah, Michel Eid [UNIFESP]
dc.contributor.institutionUniv Bonn
dc.contributor.institutionUniv Marburg
dc.contributor.institutionAvastin Data Base Bonn
dc.contributor.institutionTriemli Hosp
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionAsklepios Clin
dc.contributor.institutionEye Clin
dc.date.accessioned2016-01-24T14:06:06Z
dc.date.available2016-01-24T14:06:06Z
dc.date.issued2011-02-01
dc.description.abstractPurpose: To determine the incidence of rhegmatogenous retinal detachments (RD) after intravitreal injection in six high-volume centres.Methods: A consecutive, interventional, multicenter case series measured the incidence of RD in patients receiving intravitreal anti-VEGF. A total of 35 942 intravitreal anti-VEGF injections (the number of the injections determined by review of injection log books over a 3 year period) were performed under sterile conditions with the patient in a supine position. Injections were given 3.5-4.0 mm behind the limbus in a tunnelled fashion.Results: During 36 consecutive months, five RD were reported, between 2 and 6 days after the injection. of the affected eyes, four were myopic) 1.75 to) -5.5 dpt. the incidence rate of rhegmatogenous RD was 0.013% (5/35 942) per injection.Conclusions: the incidence of RD in our community setting was very low (1 per 7188 injections). All RD occurred during the early postoperative period. the risks of RD can be minimized by a careful injection technique.en
dc.description.affiliationUniv Bonn, Dept Ophthalmol, D-53127 Bonn, Germany
dc.description.affiliationUniv Marburg, Dept Ophthalmol, Marburg, Germany
dc.description.affiliationAvastin Data Base Bonn, Bonn, Germany
dc.description.affiliationTriemli Hosp, Dept Ophthalmol, Zurich, Switzerland
dc.description.affiliationUniversidade Federal de São Paulo, Vis Inst IPEPO, São Paulo, Brazil
dc.description.affiliationAsklepios Clin, Dept Ophthalmol, Hamburg, Germany
dc.description.affiliationEye Clin, Duisburg, Germany
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Vis Inst IPEPO, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipPan-American Association of Ophthalmology/Pan-American Ophthalmologic Foundation
dc.description.sponsorshipDeutsche Ophthalmologische Gesellschaft (DOG)
dc.description.sponsorshipFehr Foundation, Marburg
dc.format.extent70-75
dc.identifierhttp://dx.doi.org/10.1111/j.1755-3768.2010.02064.x
dc.identifier.citationActa Ophthalmologica. Malden: Wiley-Blackwell Publishing, Inc, v. 89, n. 1, p. 70-75, 2011.
dc.identifier.doi10.1111/j.1755-3768.2010.02064.x
dc.identifier.issn1755-375X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/33393
dc.identifier.wosWOS:000286628100039
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofActa Ophthalmologica
dc.rightsAcesso aberto
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.subjectadverse eventsen
dc.subjectiatrogenic damageen
dc.subjectintravitreal injectionen
dc.subjectneedleen
dc.subjectora serrataen
dc.subjectrhegmatogenous retinal detachmentsen
dc.titleIncidence of rhegmatogenous retinal detachments after intravitreal antivascular endothelial factor injectionsen
dc.typeArtigo
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