What do Cochrane systematic reviews say about diabetic retinopathy?

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dc.citation.issue1
dc.citation.volume135
dc.contributor.authorMozetic, Vania [UNIFESP]
dc.contributor.authorDaou, Julia Pozzetti [UNIFESP]
dc.contributor.authorMartimbianco, Ana Luiza Cabrera [UNIFESP]
dc.contributor.authorRiera, Rachel [UNIFESP]
dc.coverageSao Paulo
dc.date.accessioned2020-07-31T12:46:45Z
dc.date.available2020-07-31T12:46:45Z
dc.date.issued2017
dc.description.abstractCONTEXT AND OBJECTIVE: Diabetic retinopathy is a disease caused by increased permeability of retinal vessels. Its incidence and prevalence have been increasing due to urbanization, greater life expectancy and the habits of modern life. Its onset is insidious and it may lead to blindness in 75% of individuals who have been diabetic for more than 20 years. The aim here was to evaluate the evidence from Cochrane systematic reviews on interventions relating to diabetic retinopathy. DESIGN AND SETTING: Review of systematic reviews, conducted at Cochrane Brazil. METHODS: We included Cochrane systematic reviews on interventions relating to diabetic retinopathy. Two researchers evaluated the inclusion criteria, summarized the reviews and presented the results narratively. RESULTS: Ten reviews met the inclusion criteria. They showed some evidence of benefits from: (a) photocoagulation for diabetic retinopathyen
dc.description.abstract(b) strict glucose and pressure control for postponing the onset of retinopathyen
dc.description.abstract(c) antiangiogenic drugs for macular edema (high-quality evidence)en
dc.description.abstract(d) anti-vascular endothelial growth factor agents for proliferative diabetic retinopathy (very low to low-quality evidence)en
dc.description.abstractand (e) intravitreal injection or surgical implantation for treating persistent or refractory macular edema. However, blood pressure control seems to have no benefit after the onset of retinopathy. CONCLUSION: Only a few options are likely to be effective for treating diabetic retinopathy. These include photocoagulation and anti-vascular endothelial growth factor agents. Strict glucose and pressure control seem to postpone the onset of retinopathy. For macular edema, antiangiogenic drugs, intravitreal injection and surgical implantation seem to have some benefit.en
dc.description.affiliationUniv Fed Sao Paulo Unifesp, Discipline Evidence Based Med, EPM, Sao Paulo, Brazil
dc.description.affiliationHosp Dante Pazzanese Cardiol, Dyslipidemia Serv, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo Unifesp, Evidence Based Hlth Program, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo Unifesp, Med, EPM, Sao Paulo, SP, Brazil
dc.description.affiliationCochrane Brazil, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespEscola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), São Paulo (SP), Brazil
dc.description.affiliationUnifespDiscipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp)
dc.description.affiliationUnifespEvidence-Based Health Program, Universidade Federal de São Paulo (Unifesp), São Paulo (SP), Brazil
dc.description.affiliationUnifespCochrane Brazil, São Paulo (SP), Brazil
dc.description.sourceWeb of Science
dc.format.extent79-87
dc.identifierhttp://dx.doi.org/10.1590/1516-3180.2016.0356040117
dc.identifier.citationSao Paulo Medical Journal. Sao Paulo, v. 135, n. 1, p. 79-87, 2017.
dc.identifier.doi10.1590/1516-3180.2016.0356040117
dc.identifier.fileS1516-31802017000100079.pdf
dc.identifier.issn1516-3180
dc.identifier.scieloS1516-31802017000100079
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56341
dc.identifier.wosWOS:000398127000013
dc.language.isoeng
dc.publisherAssociacao Paulista Medicina
dc.relation.ispartofSao Paulo Medical Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectReview [publication type]en
dc.subjectDiabetic retinopathyen
dc.subjectTherapeuticsen
dc.subjectEvidence-based medicineen
dc.subjectEvidence-based practiceen
dc.titleWhat do Cochrane systematic reviews say about diabetic retinopathy?en
dc.typeinfo:eu-repo/semantics/article
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