High rate of Candida deep-seated infection in patients under chronic hemodialysis with extended central venous catheter use

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dc.citation.issue2
dc.citation.volume33
dc.contributor.authorOurives, Ana Paula Jafet [UNIFESP]
dc.contributor.authorGoncalves, Sarah Santos [UNIFESP]
dc.contributor.authorSiqueira, Ricardo Andreotti [UNIFESP]
dc.contributor.authorSouza, Ana Carolina Remondi [UNIFESP]
dc.contributor.authorCanziani, Maria Eugenia Fernandes [UNIFESP]
dc.contributor.authorManfredi, Silvia Regina [UNIFESP]
dc.contributor.authorCorrea, Luci [UNIFESP]
dc.contributor.authorColombo, Arnaldo Lopes [UNIFESP]
dc.coverageBilbao
dc.date.accessioned2020-07-22T13:23:05Z
dc.date.available2020-07-22T13:23:05Z
dc.date.issued2016
dc.description.abstractBackground: Hemodialysis has been described as an important risk factor for the development of candidemia in patients suffering from chronic renal failure. Aims: The aim of this study was to evaluate the epidemiology of candidemia in outpatients with renal replacement therapy (RRT) by hemodialysis where the fungemia clearly represents a healthcare associated infection. Methods: We retrospectively collected clinical and laboratory data from patients undergoing at least 3 months of RRT by hemodialysis who developed candidemia within 48 h of hospital admission. Results: We identified 14 patients with candidemia with central venous catheters (CVC) in place for 11-277 days before developing fungemia. Deep-seated infection was documented in 6 out of 14 candidiasis cases (43%), including 5 cases of endocarditis (36%). Conclusions: CVC in patients under RRT should be promptly replaced by fistulas and grafts to avoid bloodstream infections. Facing a case of candidemia, adequate source control and prompt initiation of antifungal therapy are mandatory to avoid morbidity and mortality. (C) 2016 Asociacion Espafiola de Micologia. Published by Elsevier Espatia, S.L.U. All rights reserved.en
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Disciplina Infectol, Lab Especial Micol, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Disciplina Nefrol, Sao Paulo, SP, Brazil
dc.description.affiliationHosp Rim & Hipertensao, Fundacao Oswaldo Ramos, Sao Paulo, SP, Brazil
dc.description.affiliationHosp Israelita Albert Einstein, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Escola Paulista Med, Disciplina Infectol, Lab Especial Micol, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Escola Paulista Med, Disciplina Nefrol, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Brazil
dc.description.sponsorshipCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES), Brazil
dc.description.sponsorshipIDFAPESP: 2012/04767-1
dc.description.sponsorshipIDFAPESP: 2012/04769-4
dc.description.sponsorshipIDCNPq: 308011/2010-4
dc.description.sponsorshipIDCAPES: PNPD 23038.007393/2011-11
dc.format.extent100-103
dc.identifierhttp://dx.doi.org/10.1016/j.riam.2015.10.002
dc.identifier.citationRevista Iberoamericana De Micologia. Bilbao, v. 33, n. 2, p. 100-103, 2016.
dc.identifier.doi10.1016/j.riam.2015.10.002
dc.identifier.issn1130-1406
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56031
dc.identifier.wosWOS:000380179400005
dc.language.isoeng
dc.publisherAsociacion Espanola Micologia-Aem
dc.relation.ispartofRevista Iberoamericana De Micologia
dc.rightsAcesso restrito
dc.subjectCommunity acquired candidemiaen
dc.subjectHemodialysisen
dc.subjectCandidemiaen
dc.subjectCandida parapsilosisen
dc.titleHigh rate of Candida deep-seated infection in patients under chronic hemodialysis with extended central venous catheter useen
dc.typeArtigo
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