Effect of smoking habits on sleep

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dc.contributor.authorConway, Silvia Goncalves [UNIFESP]
dc.contributor.authorRoizenblatt, Suely [UNIFESP]
dc.contributor.authorPalombini, Luciana [UNIFESP]
dc.contributor.authorCastro, Laura de Siqueira [UNIFESP]
dc.contributor.authorBittencourt, Lia Rita Azeredo [UNIFESP]
dc.contributor.authorSantos-Silva, Rogerio [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.institutionInstituto do Sono - Associação Fundo de Incentivo à Psicofarmacologia
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:38:39Z
dc.date.available2015-06-14T13:38:39Z
dc.date.issued2008-08-01
dc.description.abstractTo evaluate the effect of smoking habits on sleep, data from 1492 adults referred to the Sleep Institute were accessed and divided into 3 categories of smoking status: current, former and non-smokers. Categories of pack-years (<15 and ≥15) defined smoking severity. The association of smoking status and smoking severity with sleep was analyzed for sleep parameters, especially apnea and hypopnea index (AHI) ≥5, more than 5% of total sleep time (TST) spent with oxyhemoglobin saturation (SaO2) <90%, and arousal index. The arousal index was higher among current (21 ± 17) and former smokers (20 ± 17) than non-smokers (17 ± 15; P < 0.04). Former smokers had a higher percent of TST at SaO2 <90% than non-smokers (9 ± 18 vs 6 ± 13; P < 0.04). Former smokers with pack-years ≥15 compared to <15 exhibited higher AHI (22 ± 24 vs 16 ± 21; P < 0.05) and arousal index (22 ± 19 vs 18 ± 15; P < 0.05). Current smokers with pack-years ≥15 compared to <15 exhibited higher arousal index (23 ± 18 vs 18 ± 16; P < 0.05) and percent of TST at SaO2 <90% (11 ± 17 vs 6 ± 13; P < 0.05). Smoking status and pack-years were not associated with AHI ≥5 on logistic regression analysis, but current smokers with pack-years ≥15 were 1.9 times more likely to spend more than 5% of TST at SaO2 <90% than non-smokers (95%CI = 1.21-2.97; P = 0.005). The variability of arousal index was influenced by gender, AHI and current smokers with pack-years ≥15 (all P < 0.01). Smoking habits seem to be associated with arousal and oxyhemoglobin desaturation during sleep, but not with AHI. The effect was more pronounced in current than former smokers.en
dc.description.affiliationInstituto do Sono - Associação Fundo de Incentivo à Psicofarmacologia
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Psicobiologia
dc.description.affiliationUnifespUNIFESP, EPM, Depto. de Psicobiologia
dc.description.sourceSciELO
dc.format.extent722-727
dc.identifierhttps://dx.doi.org/10.1590/S0100-879X2008000800014
dc.identifier.citationBrazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 41, n. 8, p. 722-727, 2008.
dc.identifier.doi10.1590/S0100-879X2008000800014
dc.identifier.fileS0100-879X2008000800014.pdf
dc.identifier.issn0100-879X
dc.identifier.scieloS0100-879X2008000800014
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/4487
dc.identifier.wosWOS:000259282600014
dc.language.isoeng
dc.publisherAssociação Brasileira de Divulgação Científica
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSmokingen
dc.subjectTobaccoen
dc.subjectSmoking cessationen
dc.subjectSleepen
dc.subjectSleep-disordered breathingen
dc.titleEffect of smoking habits on sleepen
dc.typeinfo:eu-repo/semantics/article
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