Waist circumference as a predictor of mortality in peritoneal dialysis patients: a follow-up study of 48 months

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dc.citation.issue9
dc.citation.volume117
dc.contributor.authorCastro, Ana Catarina M. [UNIFESP]
dc.contributor.authorBazanelli, Ana Paula [UNIFESP]
dc.contributor.authorNerbass, Fabiana B.
dc.contributor.authorCuppari, Lilian [UNIFESP]
dc.contributor.authorKamimura, Maria A. [UNIFESP]
dc.coverageCambridge
dc.date.accessioned2020-07-13T11:53:20Z
dc.date.available2020-07-13T11:53:20Z
dc.date.issued2017
dc.description.abstractBody-fat gain is a common finding among peritoneal dialysis (PD) patients, and the accumulation of adipose tissue occurs predominantly in the abdominal area. Waist circumference (WC) is a reliable marker of abdominal obesity and its association with worse outcomes has been demonstrated in non-dialysis and haemodialysis patients. We aimed at investigating whether WC measurements as well as the changes over time in WC were able to predict mortality in PD patients. This prospective study included 109 patients undergoing PD (57 % male, age 52 (sd 16) years, 32 % diabetics, 48 % BMI25 kg/m(2)). WC was measured at the umbilicus level (empty abdominal cavity), and values >88 cm for women and >102 cm for men were considered high. Nutritional status and laboratory parameters were also evaluated. WC was measured at baseline and after 6 months, and mortality was registered during a period of 48 months. High WC was observed in 55 % of women and in 23 % of men at baseline. After 6 months, 61 % of the patients showed an increased WC. At the end of the study, twenty-seven deaths were registered. A significant increase in WC was observed only in the non-survivor group. In the Cox regression analysis adjusting for sex, age, duration on dialysis, diabetes, BMI, serum albumin and C-reactive protein, high WC at baseline as well as the 6-month increase in WC were independently associated with mortality. This study demonstrated that a high WC and the increase over time in WC were both predictors of mortality in PD patients.en
dc.description.affiliationUniv Fed Sao Paulo, Nutr Program, BR-04038002 Sao Paulo, Brazil
dc.description.affiliationProrim Fdn, Nutr Dept, Div Nephrol, BR-80215901 Joinville, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Div Nephrol, BR-04038002 Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Nutr Program, BR-04038002 Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Div Nephrol, BR-04038002 Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior
dc.description.sponsorshipFAPESP
dc.description.sponsorshipOswaldo Ramos Foundation
dc.description.sponsorshipIDFAPESP: 06/56124-6
dc.format.extent1299-1303
dc.identifierhttp://dx.doi.org/10.1017/S0007114517001179
dc.identifier.citationBritish Journal Of Nutrition. Cambridge, v. 117, n. 9, p. 1299-1303, 2017.
dc.identifier.doi10.1017/S0007114517001179
dc.identifier.issn0007-1145
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54543
dc.identifier.wosWOS:000404364300010
dc.language.isoeng
dc.publisherCambridge Univ Press
dc.relation.ispartofBritish Journal Of Nutrition
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectWaist circumferenceen
dc.subjectAbdominal obesityen
dc.subjectPeritoneal dialysisen
dc.subjectChronic kidney diseaseen
dc.subjectMortalityen
dc.titleWaist circumference as a predictor of mortality in peritoneal dialysis patients: a follow-up study of 48 monthsen
dc.typeinfo:eu-repo/semantics/article
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