Acute pancreatitis in pediatrics: a systematic review of the literature

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dc.contributor.authorMekitarian Filho, Eduardo [UNIFESP]
dc.contributor.authorCarvalho, Werther Brunow de [UNIFESP]
dc.contributor.authorSilva, Felipe Duarte
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionHosp Israelite Albert Einstein
dc.contributor.institutionHosp Santa Catarina
dc.date.accessioned2016-01-24T14:26:51Z
dc.date.available2016-01-24T14:26:51Z
dc.date.issued2012-03-01
dc.description.abstractObjective: To describe the main epidemiological, clinical, diagnostic and treatment aspects of children with acute pancreatitis.Sources: Systematic review of MEDLINE and SciELO databases in the last 5 years about acute pancreatitis in children, as well as consultation of relevant references on the texts obtained.Summary of the findings: Cases of acute pancreatitis in children have received growing attention in recent years, and an increase in the number of cases has been reported in several studies. the main etiologies in children involve biliary disease, drug-induced pancreatitis, recurrent hereditary pancreatitis and trauma, and up to 30% of cases have no defined etiology. the diagnosis is based on the combination of clinical and laboratory aspects with the increase of acinar enzymes and radiologic tests. Initial support treatment, with proper volume replacement and correction of the metabolic disturbances, besides specific nutritional therapy, are the fundamental points in the handling of acute conditions. Long term complications are unusual, and mortality rates are inferior to the rates for the adult population.Conclusions: the early diagnosis and the appropriate handling can contribute to a better outcome for the child with pancreatitis and to prevent the immediate and late complications related to the disease. More studies are required to better explain aspects related to the clinical and radiological diagnosis of pancreatitis in children, as well as aspects related to the nutritional therapy for this age group.en
dc.description.affiliationUniv São Paulo, Fac Med, Hosp Clin, Inst Crianca, BR-05403000 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, BR-05403000 São Paulo, Brazil
dc.description.affiliationHosp Israelite Albert Einstein, Unidade Pronto Atendimento, São Paulo, Brazil
dc.description.affiliationHosp Santa Catarina, Unidade Terapia Intens Pediat, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, EPM, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent101-114
dc.identifierhttp://dx.doi.org/10.2223/JPED.2163
dc.identifier.citationJornal de Pediatria. Rio de Janeiro, Rj: Soc Brasil Pediatria, v. 88, n. 2, p. 101-114, 2012.
dc.identifier.doi10.2223/JPED.2163
dc.identifier.fileS0021-75572012000200002-en.pdf
dc.identifier.fileS0021-75572012000200002-pt.pdf
dc.identifier.issn0021-7557
dc.identifier.scieloS0021-75572012000200002
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34653
dc.identifier.wosWOS:000303906000002
dc.language.isoeng
dc.publisherSoc Brasil Pediatria
dc.relation.ispartofJornal de Pediatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPancreatitisen
dc.subjectpediatricsen
dc.subjectnutritional supporten
dc.subjectmorbidityen
dc.subjectenteral nutritionen
dc.titleAcute pancreatitis in pediatrics: a systematic review of the literatureen
dc.title.alternativePancreatite aguda em pediatria: revisão sistemática da literaturapt
dc.typeinfo:eu-repo/semantics/article
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