Comparison of the effects of continuous positive airway pressure, oral appliance and exercise training in obstructive sleep apnea syndrome

Página do item simplificado
dc.contributor.authorSchutz, Teresa Cristina Barros [UNIFESP]
dc.contributor.authorCunha, Thays Crosara Abrahao [UNIFESP]
dc.contributor.authorMoura-Guimaraes, Thais [UNIFESP]
dc.contributor.authorLuz, Gabriela Pontes [UNIFESP]
dc.contributor.authorAckel-D'elia, Carolina [UNIFESP]
dc.contributor.authorAlves, Eduardo da Silva [UNIFESP]
dc.contributor.authorPantiga Junior, Gilberto [UNIFESP]
dc.contributor.authorMello, Marco Tulio de [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorBittencourt, Lia Rita Azeredo [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:45:13Z
dc.date.available2015-06-14T13:45:13Z
dc.date.issued2013-01-01
dc.description.abstractOBJECTIVE: There are several treatments for obstructive sleep apnea syndrome, such as weight loss, use of an oral appliance and continuous positive airway pressure, that can be used to reduce the signs and symptoms of obstructive sleep apnea syndrome. Few studies have evaluated the effectiveness of a physical training program compared with other treatments. The aim of this study was to assess the effects of physical exercise on subjective and objective sleep parameters, quality of life and mood in obstructive sleep apnea patients and to compare these effects with the effects of continuous positive airway pressure and oral appliance treatments. METHODS: Male patients with moderate to severe obstructive sleep apnea and body mass indices less than 30 kg/m2 were randomly assigned to three groups: continuous positive airway pressure (n = 9), oral appliance (n = 9) and physical exercise (n = 7). Polysomnographic recordings, blood samples and daytime sleepiness measurements were obtained prior to and after two months of physical exercise or treatment with continuous positive airway pressure or an oral appliance. Clinicaltrials.gov: NCT01289392 RESULTS: After treatment with continuous positive airway pressure or an oral appliance, the patients presented with a significant reduction in the apnea-hypopnea index. We did not observe changes in the sleep parameters studied in the physical exercise group. However, this group presented reductions in the following parameters: T leukocytes, very-low-density lipoprotein and triglycerides. Two months of exercise training also had a positive impact on subjective daytime sleepiness. CONCLUSIONS: Our results suggest that isolated physical exercise training was able to modify only subjective daytime sleepiness and some blood measures. Continuous positive airway pressure and oral appliances modified the apnea-hypopnea index.en
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Departamento de Psicobiologia
dc.description.affiliationUnifespUNIFESP, Depto. de Psicobiologia
dc.description.sourceSciELO
dc.description.sponsorshipAFIP
dc.description.sponsorshipCEPE
dc.description.sponsorshipCEMSA
dc.description.sponsorshipCNPq
dc.description.sponsorshipFAPESP
dc.description.sponsorshipID2009/01031-1 e 98/14303-3
dc.format.extent1168-1174
dc.identifierhttp://dx.doi.org/10.6061/clinics/2013(08)17
dc.identifier.citationClinics. Faculdade de Medicina / USP, v. 68, n. 8, p. 1168-1174, 2013.
dc.identifier.doi10.6061/clinics/2013(08)17
dc.identifier.fileS1807-59322013000801168.pdf
dc.identifier.issn1807-5932
dc.identifier.scieloS1807-59322013000801168
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/7573
dc.identifier.wosWOS:000324496600017
dc.language.isoeng
dc.publisherFaculdade de Medicina / USP
dc.relation.ispartofClinics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectObstructive Sleep Apneaen
dc.subjectCPAPen
dc.subjectOAen
dc.subjectExercise Trainingen
dc.subjectSubjective Daytime Sleepinessen
dc.subjectPolysomnographyen
dc.titleComparison of the effects of continuous positive airway pressure, oral appliance and exercise training in obstructive sleep apnea syndromeen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
S1807-59322013000801168.pdf
Tamanho:
332.3 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Coleções
EPM - Artigos