Role of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer

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dc.citation.issue35
dc.citation.volume22
dc.contributor.authorda Silva Oliveira, Kelly Cristina
dc.contributor.authorThomaz Araujo, Taissa Maira
dc.contributor.authorAlbuquerque, Camila Inagaki
dc.contributor.authorBarata, Gabriela Alcantara
dc.contributor.authorGigek, Carolina Oliveira [UNIFESP]
dc.contributor.authorLeal, Mariana Ferreira [UNIFESP]
dc.contributor.authorWisnieski, Fernanda [UNIFESP]
dc.contributor.authorRodrigues Mello Junior, Fernando Augusto
dc.contributor.authorKhayat, Andre Salim
dc.contributor.authorde Assumpcao, Paulo Pimentel
dc.contributor.authorRodriguez Burbano, Rommel Mario
dc.contributor.authorSmith, Marilia de Arruda Cardoso [UNIFESP]
dc.contributor.authorCalcagno, Danielle Queiroz
dc.coveragePleasanton
dc.date.accessioned2020-07-31T12:47:48Z
dc.date.available2020-07-31T12:47:48Z
dc.date.issued2016
dc.description.abstractAlterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic miRNAs and downregulated tumour-suppressor miRNAs in this type of cancer. In this review, we provide an overview of the role of miRNAs, pointing to their potential to be useful as diagnostic and/or prognostic biomarkers in gastric cancer. Moreover, we discuss the influence of polymorphisms and epigenetic modifications on miRNA activity.en
dc.description.affiliationFed Univ Para, Hosp Univ Joao de Barros Barreto, Nucleo Pesquisas Oncol, 2 Piso UNACON,Av Mundurucus, BR-66073000 Belem, PA, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Morfol & Genet, Disciplina Genet, BR-04021001 Sao Paulo, Brazil
dc.description.affiliationFed Univ Para, Lab Citogenet Humana, Inst Ciencias Biol, BR-66073000 Belem, PA, Brazil
dc.description.affiliationUnifespDisciplina de Genética, Departamento de Morfologia e Genética, Universidade Federal de São Paulo, São Paulo 04021-001, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent7951-7962
dc.identifierhttp://dx.doi.org/10.3748/wjg.v22.i35.7951
dc.identifier.citationWorld Journal Of Gastroenterology. Pleasanton, v. 22, n. 35, p. 7951-7962, 2016.
dc.identifier.doi10.3748/wjg.v22.i35.7951
dc.identifier.fileWOS000383981800008.pdf
dc.identifier.issn1007-9327
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57102
dc.identifier.wosWOS:000383981800008
dc.language.isoeng
dc.publisherBaishideng Publishing Group Inc
dc.relation.ispartofWorld Journal Of Gastroenterology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGastric canceren
dc.subjectEpigeneticen
dc.subjectDiagnostic biomarkersen
dc.subjectmiRNAsen
dc.subjectPrognostic biomarkersen
dc.titleRole of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric canceren
dc.typeinfo:eu-repo/semantics/article
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