LED (660 nm) and laser (670 nm) use on skin flap viability: angiogenesis and mast cells on transition line

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dc.contributor.authorNishioka, Michele Akemi [UNIFESP]
dc.contributor.authorPinfildi, Carlos Eduardo [UNIFESP]
dc.contributor.authorSheliga, Tatiana Rodrigues [UNIFESP]
dc.contributor.authorArias, Victor Eduardo [UNIFESP]
dc.contributor.authorGomes, Heitor Carvalho [UNIFESP]
dc.contributor.authorFerreira, Lydia Masako [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:27:36Z
dc.date.available2016-01-24T14:27:36Z
dc.date.issued2012-09-01
dc.description.abstractSkin flap procedures are commonly used in plastic surgery. Failures can follow, leading to the necrosis of the flap. Therefore, many studies use LLLT to improve flap viability. Currently, the LED has been introduced as an alternative to LLLT. the objective of this study was to evaluate the effect of LLLT and LED on the viability of random skin flaps in rats. Forty-eight rats were divided into four groups, and a random skin flap (10 x 4 cm) was performed in all animals. Group 1 was the sham group; group 2 was submitted to LLLT 660 nm, 0.14 J; group 3 with LED 630 nm, 2.49 J, and group 4 with LLLT 660 nm, with 2.49 J. Irradiation was applied after surgery and repeated on the four subsequent days. On the 7th postoperative day, the percentage of flap necrosis was calculated and skin samples were collected from the viable area and from the transition line of the flap to evaluate blood vessels and mast cells. the percentage of necrosis was significantly lower in groups 3 and 4 compared to groups 1 and 2. Concerning blood vessels and mast cell numbers, only the animals in group 3 showed significant increase compared to group 1 in the skin sample of the transition line. LED and LLLT with the same total energies were effective in increasing viability of random skin flaps. LED was more effective in increasing the number of mast cells and blood vessels in the transition line of random skin flaps.en
dc.description.affiliationUniversidade Federal de São Paulo, BR-04024900 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Phys Therapy, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Pathol, BR-04024900 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, BR-04024900 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Phys Therapy, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Pathol, BR-04024900 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1045-1050
dc.identifierhttps://dx.doi.org/10.1007/s10103-011-1042-7
dc.identifier.citationLasers in Medical Science. London: Springer London Ltd, v. 27, n. 5, p. 1045-1050, 2012.
dc.identifier.doi10.1007/s10103-011-1042-7
dc.identifier.issn0268-8921
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/35206
dc.identifier.wosWOS:000307406500021
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofLasers in Medical Science
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.subjectLEDen
dc.subjectLLLTen
dc.subjectSurgical flapsen
dc.subjectAngiogenesisen
dc.subjectMast cellen
dc.subjectNecrosisen
dc.titleLED (660 nm) and laser (670 nm) use on skin flap viability: angiogenesis and mast cells on transition lineen
dc.typeinfo:eu-repo/semantics/article
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