Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials

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dc.contributor.authorAndrade, Eric Pinheiro [UNIFESP]
dc.contributor.authorBerezovsky, Adriana [UNIFESP]
dc.contributor.authorSacai, Paula Yuri [UNIFESP]
dc.contributor.authorPereira, Josenilson Martins [UNIFESP]
dc.contributor.authorRocha, Daniel Martins [UNIFESP]
dc.contributor.authorSalomao, Solange Rios [UNIFESP]
dc.date.accessioned2019-07-22T15:46:42Z
dc.date.available2019-07-22T15:46:42Z
dc.date.issued2016
dc.description.abstractPurpose: To evaluate visual acuity and transient pattern reversal (PR) visual evoked potentials (VEPs) in the fellow eyes of children with strabismic and/or anisometropic amblyopia. Methods: Children diagnosed with strabismic and/or anisometropic amblyopia were recruited for electrophysiological assessment by VEPs. Monocular grating and optotype acuity were measured using sweep-VEPs and an Early Treatment Diabetic Retinopathy Study chart, respectively. During the same visit, transient PR-VEPs of each eye were recorded using stimuli subtending with a visual angle of 60', 15', and 7.5'. Parameters of amplitude (in mu V) and latency (in ms) were determined from VEP recordings. Results: A group of 40 strabismic and/or anisometropic amblyopic children (22 females: 55%, mean age = 8.7 +/- 2.2 years, median = 8 years) was examined. A control group of 19 healthy children (13 females: 68.4%, mean age = 8.2 +/- 2.6 years, median = 8 years) was also included. The fellow eyes of all amblyopes had significantly worse optotype acuity (p = 0.021) than the control group, regardless of whether they were strabismic (p = 0.040) or anisometropic (p = 0.048). Overall, grating acuity was significantly worse in the fellow eyes of amblyopes (p = 0.016) than in healthy controls. Statistically prolonged latency for visual angles of 15' and 7.5' (p = 0.018 and 0.002, respectively) was found in the strabismic group when compared with the control group. For the smaller visual stimulus (7.5'), statistically prolonged latency was found among all fellow eyes of amblyopic children (p< 0.001). Conclusions: The fellow eyes of amblyopic children showed worse optotype and grating acuity, with subtle abnormalities in the PR-VEP detected as prolonged latencies for smaller size stimuli when compared with eyes of healthy children. These findings show the deleterious effects of amblyopia in several distinct visual functions, mainly those related to spatial vision.en
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, Dept Opththalmol & Visual Sci, EPM, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, Dept Opththalmol & Visual Sci, EPM, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent294-298
dc.identifierhttp://dx.doi.org/10.5935/0004-2749.20160085
dc.identifier.citationArquivos Brasileiros De Oftalmologia. Sao Paulo, v. 79, n. 5, p. 294-298, 2016.
dc.identifier.doi10.5935/0004-2749.20160085
dc.identifier.fileS0004-27492016000500294.pdf
dc.identifier.issn0004-2749
dc.identifier.scieloS0004-27492016000500294
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/51036
dc.identifier.wosWOS:000391431500004
dc.language.isoeng
dc.publisherConsel Brasil Oftalmologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectVisual acuityen
dc.subjectEvoked potentialsen
dc.subjectvisualen
dc.subjectElectrophysiologyen
dc.subjectAmblyopiaen
dc.subjectRefractive errorsen
dc.subjectChilden
dc.titleDysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentialsen
dc.title.alternativeAlterações dos potenciais visuais evocados nos olhos contralaterais de crianças com ambliopia estrabísmica e anisometrópicapt
dc.typeinfo:eu-repo/semantics/article
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