Treatment of Obese Adolescents: the Influence of Periodization Models and ACE Genotype

dc.contributor.authorFoschini, Denis [UNIFESP]
dc.contributor.authorAraújo, Ronaldo de Carvalho [UNIFESP]
dc.contributor.authorBacurau, Reury Frank Pereira
dc.contributor.authorPiano, Aline de [UNIFESP]
dc.contributor.authorAlmeida, Sandro Soares de [UNIFESP]
dc.contributor.authorCarnier, June [UNIFESP]
dc.contributor.authorRosa, Thiago dos Santos [UNIFESP]
dc.contributor.authorMello, Marco Tulio de [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorDâmaso, Ana Raimunda [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2016-01-24T13:59:28Z
dc.date.available2016-01-24T13:59:28Z
dc.date.issued2010-04-01
dc.description.abstractThe aims of the present study were to compare the effects of two periodization models on metabolic syndrome risk factors in obese adolescents and verify whether the angiotensin-converting enzyme (ACE) genotype is important in establishing these effects. A total of 32 postpuberty obese adolescents were submitted to aerobic training (AT) and resistance training (RT) for 14 weeks. the subjects were divided into linear periodization (LP, n = 16) or daily undulating periodization (DUP, n = 16). Body composition, visceral and subcutaneous fat, glycemia, insulinemia, homeostasis model assessment of insulin resistance (HOMA-IR), lipid profiles, blood pressure, maximal oxygen consumption (VO(2max)), resting metabolic rate (RMR), muscular endurance were analyzed at baseline and after intervention. Both groups demonstrated a significant reduction in body mass, BMI, body fat, visceral and subcutaneous fat, total and low-density lipoprotein cholesterol, blood pressure and an increase in fat-free mass, VO(2max), and muscular endurance. However, only DUP promoted a reduction in insulin concentrations and HOMA-IR. It is important to emphasize that there was no statics difference between LP and DUP groups; however, it appears that there may be bigger changes in the DUP than LP group in some of the metabolic syndrome risk factors in obese adolescents with regard to the effect size (ES). Both periodization models presented a large effect on muscular endurance. Despite the limitation of sample size, our results suggested that the ACE genotype may influence the functional and metabolic characteristics of obese adolescents and may be considered in the future strategies for massive obesity control.en
dc.description.affiliationUniversidade Federal de São Paulo, Post Grad Program Nutr, Paulista Med Sch, UNIFESP EPM, São Paulo, Brazil
dc.description.affiliationMetodista Univ São Paulo, Fac Hlth, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Biophys, Paulista Med Sch, UNIFESP EPM, São Paulo, Brazil
dc.description.affiliationEACH USP, Sch Arts Sci & Humanities, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Biosci, Paulista Med Sch, UNIFESP EPM, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psychobiol, Paulista Med Sch, UNIFESP EPM, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Post Grad Program Nutr, Paulista Med Sch, UNIFESP EPM, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Biophys, Paulista Med Sch, UNIFESP EPM, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Biosci, Paulista Med Sch, UNIFESP EPM, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psychobiol, Paulista Med Sch, UNIFESP EPM, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipAFIP
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCENESP
dc.description.sponsorshipFADA
dc.description.sponsorshipUNIFESP
dc.description.sponsorshipIDFAPESP: 2006/00684-3
dc.description.sponsorshipIDFAPESP: 2008/53069-0
dc.description.sponsorshipIDFAPESP: 9814303-3
dc.format.extent766-772
dc.identifierhttps://dx.doi.org/10.1038/oby.2009.247
dc.identifier.citationObesity. New York: Nature Publishing Group, v. 18, n. 4, p. 766-772, 2010.
dc.identifier.doi10.1038/oby.2009.247
dc.identifier.issn1930-7381
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/32388
dc.identifier.wosWOS:000276665200020
dc.language.isoeng
dc.publisherNature Publishing Group
dc.relation.ispartofObesity
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleTreatment of Obese Adolescents: the Influence of Periodization Models and ACE Genotypeen
dc.typeinfo:eu-repo/semantics/article
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