Far beyond the motor neuron: the role of glial cells in amyotrophic lateral sclerosis

Página do item simplificado
dc.citation.issue10
dc.citation.volume74
dc.contributor.authorSouza, Paulo Victor Sgobbi de [UNIFESP]
dc.contributor.authorPinto, Wladimir Bocca Vieira de Rezende [UNIFESP]
dc.contributor.authorRezende Filho, Flavio Moura [UNIFESP]
dc.contributor.authorOliveira, Acary Souza Bulle [UNIFESP]
dc.coverageSao Paulo Sp
dc.date.accessioned2020-07-31T12:47:39Z
dc.date.available2020-07-31T12:47:39Z
dc.date.issued2016
dc.description.abstractMotor neuron disease is one of the major groups of neurodegenerative diseases, mainly represented by amyotrophic lateral sclerosis. Despite wide genetic and biochemical data regarding its pathophysiological mechanisms, motor neuron disease develops under a complex network of mechanisms not restricted to the unique functions of the alpha motor neurons but which actually involve diverse functions of glial cell interaction. This review aims to expose some of the leading roles of glial cells in the physiological mechanisms of neuron-glial cell interactions and the mechanisms related to motor neuron survival linked to glial cell functions.en
dc.description.affiliationUniv Fed Sao Paulo, Dept Neurol & Neurocirurgia, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, São Paulo SP, Brasil
dc.description.sourceWeb of Science
dc.format.extent849-854
dc.identifierhttp://dx.doi.org/10.1590/0004-282X20160117
dc.identifier.citationArquivos De Neuro-Psiquiatria. Sao Paulo Sp, v. 74, n. 10, p. 849-854, 2016.
dc.identifier.doi10.1590/0004-282X20160117
dc.identifier.fileS0004-282X2016001000849.pdf
dc.identifier.issn0004-282X
dc.identifier.scieloS0004-282X2016001000849
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56975
dc.identifier.wosWOS:000386578100013
dc.language.isoeng
dc.publisherAssoc Arquivos Neuro- Psiquiatria
dc.relation.ispartofArquivos De Neuro-Psiquiatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectmotor neuronsen
dc.subjectastrocyteen
dc.subjectmicrogliaen
dc.subjectamyotrophic lateral sclerosisen
dc.subjectmotor neuron diseaseen
dc.titleFar beyond the motor neuron: the role of glial cells in amyotrophic lateral sclerosisen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
S0004-282X2016001000849.pdf
Tamanho:
799.8 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Coleções
EPM - Artigos