Persistent hyperactivity of the parathyroid glands in treated hypothyroid patients

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dc.contributor.authorFurlanetto, Reinaldo Perrone [UNIFESP]
dc.contributor.authorLazaretti-Castro, Marise [UNIFESP]
dc.contributor.authorKasamatsu, Teresa Sayoko [UNIFESP]
dc.contributor.authorBrandao, Cynthia Maria Alvares [UNIFESP]
dc.contributor.authorVieira, Jose Gilberto Henriques [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T12:39:52Z
dc.date.available2018-06-15T12:39:52Z
dc.date.issued1990-12-01
dc.description.abstractTwelve untreated hypothyroid patients were submitted to EDTA infusion and the parathyroid hormone response to the induced hypocalcemia was studied with an amino-terminal specific assay. Eight of these patients were retested 6 months after achieving clinical and laboratory euthyroidism. The PTH response in the pretreatment condition was significantly higher than that obtained in a group of 10 normal individuals; this increased response had not normalized after 6 months of euthyroidism. This persisting hyperresponsiveness can be a contributory factor to the bone hypersensitivity to thyroid hormone replacement seen in hypothyroid patients.en
dc.description.affiliationESCOLA PAULISTA MED SCH,DIV ENDOCRINOL,CP 20266,BR-04034 SAO PAULO,BRAZIL
dc.description.affiliationUnifespESCOLA PAULISTA MED SCH,DIV ENDOCRINOL,CP 20266,BR-04034 SAO PAULO,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent609-612
dc.identifierhttp://dx.doi.org/10.1530/acta.0.1230609
dc.identifier.citationActa Endocrinologica. Oslo: Scandinavian University Press, v. 123, n. 6, p. 609-612, 1990.
dc.identifier.doi10.1530/acta.0.1230609
dc.identifier.issn0001-5598
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/41995
dc.identifier.wosWOS:A1990EX77600005
dc.language.isoeng
dc.publisherScandinavian University Press
dc.relation.ispartofActa Endocrinologica
dc.rightsAcesso restrito
dc.titlePersistent hyperactivity of the parathyroid glands in treated hypothyroid patientsen
dc.typeArtigo
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