Effects of acute oxygen supplementation on functional capacity and heart rate recovery in Eisenmenger syndrome

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dc.citation.volume231
dc.contributor.authorGonzaga, Laion R. A. [UNIFESP]
dc.contributor.authorMatos-Garcia, Bruna C. [UNIFESP]
dc.contributor.authorRocco, Isadora S. [UNIFESP]
dc.contributor.authorBegot, Isis [UNIFESP]
dc.contributor.authorBolzan, Douglas W. [UNIFESP]
dc.contributor.authorTatani, Solange B. [UNIFESP]
dc.contributor.authorSantos, Vinicius B. [UNIFESP]
dc.contributor.authorSilva, Celia M. C. [UNIFESP]
dc.contributor.authorCarvalho, Antonio C. C.
dc.contributor.authorArena, Ross
dc.contributor.authorGomes, Walter J. [UNIFESP]
dc.contributor.authorGuizilini, Solange [UNIFESP]
dc.coverageClare
dc.date.accessioned2020-07-17T14:02:39Z
dc.date.available2020-07-17T14:02:39Z
dc.date.issued2017
dc.description.abstractBackground: Eisenmenger syndrome (ES) precipitates the extreme manifestation of pulmonary hypertension, which leads to severe functional limitation and poor quality of life. The propose of the current study was: 1) examined the acute effects of 40% oxygen supplementation during the 6-minute walk test (6MWT)en
dc.description.abstractand 2) evaluate the relation between exercise capacity and clinical cardiac parameters in patients with ES. Methods: Thirty subjects were prospectively includeden
dc.description.abstractall were submitted to a 6MWT with compressed air and with 40% of oxygen. Heart rate recovery at the first minute (HRR1) and perceived effort Borg scale for dyspnea and lower limb fatigue were recorded in both tests scenarios. Results: The 6MWT distance was modestly, negatively associated with pulmonary vascular resistance (PVR) [r = 0.46, p = 0.02]. Patients improved 6MWT distance (p < 0.001) and exhibited a faster HRR1 (p < 0.001) with 40% supplemental oxygen compared to compressed air. With 40% supplemental oxygen, subjects revealed lower dyspnea and lower limb fatigue compared to 6MWT without oxygen supplementation (p < 0.001). The amount of change in the 6MWT distance from air to oxygen was moderate, positively associated with tricuspid annular plane systolic excursion (TAPSE) and right ventricular fractional area change (RVFAC) [r = 0.50, p = 0.03en
dc.description.abstractr = 0.64, p < 0.001, respectively]. Conclusion: Acute 40% oxygen supplementation in patients with Eisenmenger syndrome led to an improvement in 6MWT distance, faster HRR1 and lower dyspnea and lower limb fatigue perception. Moreover, functional capacity was positively associated with right ventricular parameters. (C) 2017 Published by Elsevier Ireland Ltd.en
dc.description.affiliationUniv Fed Sao Paulo, Sao Paulo Hosp, Cardiol Discipline, Rua Napoleao de Barros 715,3 Andar, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Sao Paulo Hosp, Cardiovasc Surg Discipline, Rua Napoleao de Barros 715,3 Andar, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationFed Univ Sao Paulo Santos, Dept Human Mot Sci, Phys Therapy Sch, Rua Silva Jardim,Edificio Cent 136, BR-11015020 Santos, SP, Brazil
dc.description.affiliationUniv Illinois, Dept Phys Therapy, Coll Appl Hlth Sci, Taylor St,454 AHSB, Chicago, IL 60612 USA
dc.description.affiliationUniv Illinois, Integrat Physiol Lab, Coll Appl Hlth Sci, Taylor St,454 AHSB, Chicago, IL 60612 USA
dc.description.affiliationUnifespUniv Fed Sao Paulo, Sao Paulo Hosp, Cardiol Discipline, Rua Napoleao de Barros 715,3 Andar, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Sao Paulo Hosp, Cardiovasc Surg Discipline, Rua Napoleao de Barros 715,3 Andar, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationUnifespFed Univ Sao Paulo Santos, Dept Human Mot Sci, Phys Therapy Sch, Rua Silva Jardim,Edificio Cent 136, BR-11015020 Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent110-114
dc.identifierhttp://dx.doi.org/10.1016/j.ijcard.2017.01.025
dc.identifier.citationInternational Journal Of Cardiology. Clare, v. 231, p. 110-114, 2017.
dc.identifier.doi10.1016/j.ijcard.2017.01.025
dc.identifier.issn0167-5273
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54922
dc.identifier.wosWOS:000397905600020
dc.language.isoeng
dc.publisherElsevier Ireland Ltd
dc.relation.ispartofInternational Journal Of Cardiology
dc.rightsAcesso restrito
dc.subjectEisenmenger syndromeen
dc.subjectFunctional capacityen
dc.subjectOxygen supplementationen
dc.subjectPulmonary hypertensionen
dc.subjectCongenital heart diseaseen
dc.titleEffects of acute oxygen supplementation on functional capacity and heart rate recovery in Eisenmenger syndromeen
dc.typeArtigo
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