Diagnostic Labeling of COPD in five Latin American cities

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dc.contributor.authorTalamo, Carlos
dc.contributor.authorMontes de Oca, Maria
dc.contributor.authorHalbert, Ron
dc.contributor.authorPerez-Padilla, Rogelio
dc.contributor.authorJardim, José Roberto B. [UNIFESP]
dc.contributor.authorMuino, Adriana
dc.contributor.authorLopez, Maria Victorina
dc.contributor.authorValdivia, Gonzalo
dc.contributor.authorPertuze, Julio
dc.contributor.authorMoreno, Dolores
dc.contributor.authorMenezes, Ana Maria B.
dc.contributor.authorPLATINO Team
dc.contributor.institutionHosp Univ Caracas
dc.contributor.institutionUniv Calif Los Angeles
dc.contributor.institutionInst Resp Dis
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Republica
dc.contributor.institutionPontificia Univ Catolica Chile
dc.contributor.institutionFed Univ Pelotas
dc.date.accessioned2016-01-24T12:41:42Z
dc.date.available2016-01-24T12:41:42Z
dc.date.issued2007-01-01
dc.description.abstractBackground: COPD is a major worldwide problem with a rising prevalence. Despite its importance, there is a lack of information regarding underdiagnosis and misdiagnosis of COPD in different countries. As part of the Proyecto Latinoamericano de Investigacion en Obstruccion Pulmonar study, we examined the relationship between prior diagnostic label and airway obstruction in the metropolitan areas of five Latin American cities (S (a) over tildeo Paulo, Santiago, Mexico City, Montevideo, and Caracas).Methods: A two-stage sampling strategy was used in each of the five areas to obtain probability samples of adults aged 40 years. Participants completed a questionnaire that included questions on prior diagnoses, and prebronchodilator and postbronchodilator spirometry. A study diagnosis of COPD was based on airway obstruction, defined as a postbronchodilator FEV1/FVC < 0.70.Results: Valid spirometry and prior diagnosis information was obtained for 5,303 participants; 758 subjects had a study diagnosis of COPD, of which 672 cases (88.7%) had not been previously diagnosed. the prevalence of undiagnosed COPD was 12.7%, ranging from 6.9% in Mexico City to 18.2% in Montevideo. Among 237 subjects with a prior COPD diagnosis, only 86 subjects (36.3%) had postbronchodilator FEV1/FVC < 0.7, while 151 subjects (63.7%) had normal spirometric values. in the same group of 237 subjects, only 34% reported ever undergoing spirometry prior to our study.Conclusions: Inaccurate diagnostic labeling of COPD represents an important health problem in Latin America. One possible explanation is the low rate of spirometry for COPD diagnosis.en
dc.description.affiliationHosp Univ Caracas, Univ Cent Venezuela, Fac Med, Catedra Neumonol, Caracas 1040, Venezuela
dc.description.affiliationUniv Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90024 USA
dc.description.affiliationInst Resp Dis, Mexico City, DF, Mexico
dc.description.affiliationUniversidade Federal de São Paulo, São Paulo, Brazil
dc.description.affiliationUniv Republica, Fac Med, Montevideo, Uruguay
dc.description.affiliationPontificia Univ Catolica Chile, Santiago, Chile
dc.description.affiliationFed Univ Pelotas, Post Grad Program Epidemiol, Pelotas, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, EPM, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent60-67
dc.identifierhttp://dx.doi.org/10.1378/chest.06-1149
dc.identifier.citationChest. Northbrook: Amer Coll Chest Physicians, v. 131, n. 1, p. 60-67, 2007.
dc.identifier.doi10.1378/chest.06-1149
dc.identifier.issn0012-3692
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/29346
dc.identifier.wosWOS:000243548100012
dc.language.isoeng
dc.publisherAmer Coll Chest Physicians
dc.relation.ispartofChest
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCOPDen
dc.subjectdiagnostic errorsen
dc.subjectprevalenceen
dc.subjectspirometryen
dc.titleDiagnostic Labeling of COPD in five Latin American citiesen
dc.typeinfo:eu-repo/semantics/article
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