Epidemiologia de varizes em municípios do Estado de São Paulo
Data
2024-12-03
Autores
Burihan, Marcelo Calil 
Orientadores
Guedes Neto, Henrique Jorge
Tipo
Tese de doutorado
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Introdução: A doença venosa é de grande incidência na população mundial e de grande impacto sócio-econômico para os países, principalmente os mais pobres, mas, no Brasil, não há dados recentes. Objetivo: o trabalho teve como objetivo definir o perfil epidemiológico das varizes em municípios do Estado de São Paulo, utilizando a Classificação Clínica CEAP das Doenças Venosas dos Membros Inferiores. Material e Método: o estudo foi conduzido pela Liga Acadêmica Paulista de Cirurgia Vascular em cinco municípios entre 2015 e 2018, com 1277 participantes. Os critérios de inclusão foram pacientes adultos de ambos os sexos. Para os critérios de exclusão foram considerados menores de 20 anos, amputados, acamados, pacientes sem discernimento para preenchimento do termo de consentimento livre e esclarecido e pacientes dos ambulatórios de cirurgia vascular. A distribuição das amostras foi feita entre grupos femininos e masculinos, adultos e idosos. Resultados: a análise dos resultados revelou uma predominância de mulheres na amostra e uma prevalência significativa de varizes em populações mais velhas. A classificação CEAP indicou uma alta prevalência de casos clínicos superiores a C0, especialmente em mulheres. A etnia caucasiana mostrou-se mais prevalente em todos os grupos CEAP. Quanto ao Índice de Massa Corpórea (IMC), embora não tenha sido observada diferença significativa em algumas análises, uma correlação positiva foi encontrada entre IMC e a gravidade das varizes. A hereditariedade, especialmente a materna, pareceu ter uma correlação fraca, mas significativa com a gravidade das varizes, principalmente em mulheres. A gestação também foi associada com um aumento na gravidade das varizes. Por outro lado, o tabagismo, a atividade física, assim como o tipo de trabalho, não pareceram influenciar significativamente no desenvolvimento das varizes. Conclusão: os resultados sugerem que fatores como idade, etnia, IMC, hereditariedade e gestação podem desempenhar papéis importantes na ocorrência e gravidade das varizes.
Introduction: venous disease has a high incidence in the global population and significant socio-economic impact on countries, especially the poorest ones. However, in Brazil, recent data is lacking. Objective: this stydy aimed to define the epidemiological profile of varicose veins in municipalities in the State of São Paulo, using the CEAP Clinical Classification of Venous Diseases of the Lower Extremities. Materials and Methods: the study was conducted by the Paulista Academic League of Vascular Surgery across five municipalities between 2015 and 2018, with 1277 participants. Inclusion criteria were adult patients of both sexes. Exclusion criteria included those under 20 years of age, amputees, bedridden patients, individuals unable to complete the informed consente form, and patients from vascular surgery outpatient clinics. Sample distribution was done female and male groups,adults, and the elderly. Results: analysis of the results revealed a predominance of women in the sample and a significant prevalence of varicose veins in older populations. The CEAP classification indicated a high prevalence of clinical cases above C0, especially in women. The Caucasian ethnicity was more prevalent in all CEAP groups. Regarding Body Mass Index (BMI), although no significant difference was observed in some analyses, a positive correlation was found between BMI and the severity of varicose veins. Heredity, particulary maternal, showed a weak but significant correlation with the severity of varicose veins, especially in women. Pregnancy was also associated with an increase in the severity of varicose veins. On the other hand, smoking, physical activity and type of work did not appear to significantly influence the development of varicose veins. Conclusion: the results suggest that factors such as age, ethnicity, BMI, heredity, and pregnancy may play important roles in the occurrence and severity of varicose veins.
Introduction: venous disease has a high incidence in the global population and significant socio-economic impact on countries, especially the poorest ones. However, in Brazil, recent data is lacking. Objective: this stydy aimed to define the epidemiological profile of varicose veins in municipalities in the State of São Paulo, using the CEAP Clinical Classification of Venous Diseases of the Lower Extremities. Materials and Methods: the study was conducted by the Paulista Academic League of Vascular Surgery across five municipalities between 2015 and 2018, with 1277 participants. Inclusion criteria were adult patients of both sexes. Exclusion criteria included those under 20 years of age, amputees, bedridden patients, individuals unable to complete the informed consente form, and patients from vascular surgery outpatient clinics. Sample distribution was done female and male groups,adults, and the elderly. Results: analysis of the results revealed a predominance of women in the sample and a significant prevalence of varicose veins in older populations. The CEAP classification indicated a high prevalence of clinical cases above C0, especially in women. The Caucasian ethnicity was more prevalent in all CEAP groups. Regarding Body Mass Index (BMI), although no significant difference was observed in some analyses, a positive correlation was found between BMI and the severity of varicose veins. Heredity, particulary maternal, showed a weak but significant correlation with the severity of varicose veins, especially in women. Pregnancy was also associated with an increase in the severity of varicose veins. On the other hand, smoking, physical activity and type of work did not appear to significantly influence the development of varicose veins. Conclusion: the results suggest that factors such as age, ethnicity, BMI, heredity, and pregnancy may play important roles in the occurrence and severity of varicose veins.
Descrição
Citação
BURIHAN, Marcelo Calil. Epidemiologia de varizes em municípios do Estado de São Paulo. 2024. 125 f. Tese (Doutorado em Ciência Cirúrgica Interdisciplinar) - Escola Paulista de Medicina. Universidade Federal de São Paulo (UNIFESP). São Paulo, 2024.