High prevalence of hepatitis E virus antibodies among blood donors in Southern Brazil

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dc.citation.issue2
dc.citation.volume88
dc.contributor.authorPassos-Castilho, Ana Maria [UNIFESP]
dc.contributor.authorde Sena, Anne [UNIFESP]
dc.contributor.authorGeraldo, Alexandre
dc.contributor.authorSpada, Celso
dc.contributor.authorGranato, Celso F. H. [UNIFESP]
dc.coverageHoboken
dc.date.accessioned2020-11-03T14:40:37Z
dc.date.available2020-11-03T14:40:37Z
dc.date.issued2016
dc.description.abstractBrazil has been classified as moderately endemic for hepatitis E virus (HEV) infection. However, data on the seroprevalence of HEV in this region are limited. This study evaluated the prevalence of past or present HEV infection among blood donors in the metropolitan area of Itajai Valley, Southern Brazil, a region of predominant German heritage, where cultural habits result in a high consumption of pork. Serum samples from 300 blood donors were tested in December 2014 using serological and molecular methods. Anti-HEV IgG antibodies were detected in 30 (10%) subjects, and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Only one subject had anti-HEV IgM, whereas none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG in blood donors than previously reported in Brazil. (c) 2015 Wiley Periodicals, Inc.en
dc.description.affiliationUniv Fed Sao Paulo, Div Infect Dis, 781 Pedro Toledo St, BR-04039032 Sao Paulo, Brazil
dc.description.affiliationFleury SA Grp, Sao Paulo, Brazil
dc.description.affiliationHEMOSC Santa Catarina Hematol & Hemotherapy Ctr, Blumenau, Brazil
dc.description.affiliationUniv Fed Santa Catarina, Dept Clin Anal, Florianopolis, SC, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Div Infect Dis, 781 Pedro Toledo St, BR-04039032 Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo
dc.description.sponsorshipIDFAPESP: 2012/22925-3
dc.description.sponsorshipIDFAPESP: 2013/03701-0
dc.format.extent361-364
dc.identifierhttps://doi.org/10.1002/jmv.24336
dc.identifier.citationJournal Of Medical Virology. Hoboken, v. 88, n. 2, p. 361-364, 2016.
dc.identifier.doi10.1002/jmv.24336
dc.identifier.issn0146-6615
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/58643
dc.identifier.wosWOS:000368740500023
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofJournal Of Medical Virology
dc.rightsAcesso restrito
dc.subjecthepatitis E virusen
dc.subjectblood donorsen
dc.subjectseroprevalenceen
dc.subjectBrazilen
dc.titleHigh prevalence of hepatitis E virus antibodies among blood donors in Southern Brazilen
dc.typeArtigo
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