Use of exercise testing in the evaluation of interventional efficacy: an official ERS statement

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dc.citation.issue2
dc.citation.volume47
dc.contributor.authorPuente-Maestu, Luis
dc.contributor.authorPalange, Paolo
dc.contributor.authorCasaburi, Richard
dc.contributor.authorLaveneziana, Pierantonio
dc.contributor.authorMaltais, Francois
dc.contributor.authorNeder, J. Alberto [UNIFESP]
dc.contributor.authorO'Donnell, Denis E.
dc.contributor.authorOnorati, Paolo
dc.contributor.authorPorszasz, Janos
dc.contributor.authorRabinovich, Roberto
dc.contributor.authorRossiter, Harry B.
dc.contributor.authorSingh, Sally
dc.contributor.authorTroosters, Thierry
dc.contributor.authorWard, Susan
dc.coverageSheffield
dc.date.accessioned2020-08-21T17:00:25Z
dc.date.available2020-08-21T17:00:25Z
dc.date.issued2016
dc.description.abstractThis document reviews 1) the measurement properties of commonly used exercise tests in patients with chronic respiratory diseases and 2) published studies on their utilty and/or evaluation obtained from MEDLINE and Cochrane Library searches between 1990 and March 2015. Exercise tests are reliable and consistently responsive to rehabilitative and pharmacological interventions. Thresholds for clinically important changes in performance are available for several tests. In pulmonary arterial hypertension, the 6-min walk test (6MWT), peak oxygen uptake and ventilation/carbon dioxide output indices appear to be the variables most responsive to vasodilators. While bronchodilators do not always show clinically relevant effects in chronic obstructive pulmonary disease, high-intensity constant work-rate (endurance) tests (CWRET) are considerably more responsive than incremental exercise tests and 6MWTs. High-intensity CWRETs need to be standardised to reduce interindividual variability. Additional physiological information and responsiveness can be obtained from isotime measurements, particularly of inspiratory capacity and dyspnoea. Less evidence is available for the endurance shuttle walk test. Although the incremental shuttle walk test and 6MWT are reliable and less expensive than cardiopulmonary exercise testing, two repetitions are needed at baseline. All exercise tests are safe when recommended precautions are followed, with evidence suggesting that no test is safer than others.en
dc.description.affiliationHosp Univ Gregorio Maranon, Serv Neumol, Madrid, Spain
dc.description.affiliationInst Invest Sanitaria Gregorio Maranon, Madrid, Spain
dc.description.affiliationUniv Complutense Madrid, Fac Med, Madrid, Spain
dc.description.affiliationSapienza Univ Roma, Dipartimento Sanita Pubbl & Malattie Infett, Rome, Italy
dc.description.affiliationHarbor UCLA Med Ctr, Rehabilitat Clin Trials Ctr, Div Pulm & Crit Care Physiol & Med, Los Angeles Biomed Res Inst, Torrance, CA 90509 USA
dc.description.affiliationUniv Paris 06, Neurophysiol Resp Exp & Clin UMRS1158, Sorbonne Univ, INSERM, Paris, France
dc.description.affiliationGrp Hosp Pitie Salpetriere Charles Foix, AP HP, Serv Explorat Fonct Respirat Exercice & Dyspnee, Paris, France
dc.description.affiliationUniv Laval, Inst Univ Cardiol & Pneumol Quebec, Quebec City, PQ, Canada
dc.description.affiliationQueens Univ, Lab Clin Exercise Physiol, Div Resp & Crit Care Med, Kingston, ON, Canada
dc.description.affiliationKingston Gen Hosp, Kingston, ON, Canada
dc.description.affiliationUniv Fed Sao Paulo, Div Respirol, Clin Exercise Physiol Unit, Sao Paulo, Brazil
dc.description.affiliationQueens Univ, Resp Invest Unit, Div Resp & Crit Care Med, Kingston, ON, Canada
dc.description.affiliationASL1 Sassari, Osped Civile Alghero, Alghero, SS, Italy
dc.description.affiliationUniv Edinburgh, ELEGI Colt Lab, Ctr Inflammat Res, Queens Med Res Inst, Edinburgh, Midlothian, Scotland
dc.description.affiliationUniv Leeds, Fac Biol Sci, Leeds, W Yorkshire, England
dc.description.affiliationUniv Hosp Leciester NHS Trust, Ctr Exercise & Rehabil Sci, Glenfield Hosp, Leciester, England
dc.description.affiliationKatholieke Univ Leuven, Dept Rehabil Sci, Leuven, Belgium
dc.description.affiliationUniv Hosp Gasthuisberg, Resp Rehabil Div, Leuven, Belgium
dc.description.affiliationHuman Bioenerget Res Ctr, Crickhowell, Wales
dc.description.affiliationUnifespUniv Fed Sao Paulo, Div Respirol, Clin Exercise Physiol Unit, Sao Paulo, Brazil
dc.description.provenanceMade available in DSpace on 2020-08-21T17:00:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2016en
dc.description.sourceWeb of Science
dc.format.extent429-460
dc.identifierhttp://dx.doi.org/10.1183/13993003.00745-2015
dc.identifier.citationEuropean Respiratory Journal. Sheffield, v. 47, n. 2, p. 429-460, 2016.
dc.identifier.doi10.1183/13993003.00745-2015
dc.identifier.issn0903-1936
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57988
dc.identifier.wosWOS:000385286600016
dc.language.isoeng
dc.publisherEuropean Respiratory Soc Journals Ltd
dc.relation.ispartofEuropean Respiratory Journal
dc.rightsAcesso aberto
dc.titleUse of exercise testing in the evaluation of interventional efficacy: an official ERS statementen
dc.typeArtigo
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