Remoção de Estradiol através de processos de adsorção com AL-MCM-41
Data
2024-11-29
Autores
Zacharias, José Augusto Giusti 
Orientadores
Bresolin, Igor Tadeu Lazzarotto
Tipo
Dissertação de mestrado
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Nas últimas décadas a presença de resíduos de fármacos, principalmente disruptores endócrinos nas águas de rios, lagos e represas está chamando a atenção para os impactos na saúde humana e nos ecossistemas. Esses componentes são chamados de poluentes emergentes devido aos riscos que apresentam, mesmo estando em baixas concentrações, além da falta de legislações a respeito dos limites presentes nos efluentes. Um disruptor endócrino atua imitando ou simulando hormônios naturais do corpo, podendo atuar como antagonista, alterando seu metabolismo in vivo. Além disso, pode se ligar a um receptor dentro de uma célula e bloquear a ligação do hormônio endógeno. Ao interferir no sistema endócrino do corpo, produz efeitos adversos no desenvolvimento, reprodução, neurologia e imunidade em humanos e na vida selvagem. Diante disso, este trabalho tem como objetivo estudar o desempenho da sílica mesoporosa Al-MCM-41 (Si/Al = 10,5) na adsorção do 17β-estradiol (E2) e 17α-etinilestradiol (EE2). Os resultados de caracterização mostram que o adsorvente Al-MCM-41 sintetizado apresenta uma estrutura hexagonal ordenada com uma alta área específica em torno de 760 m2g-1. A melhor capacidade de adsorção tanto do E2 como do EE2 ocorre em pH 3,0 e atingem o equilíbrio após 60 minutos de contato. O adsorvente Al-MCM-41 apresenta um excelente desempenho de remoção dos hormônios, com qmax em torno de 84 mg E2 g-1 e 75 mg EE2 g-1.
Os estudos cinéticos e de equilíbrio mostraram o melhor ajustes dos modelos não-lineares de pseudo-primeira ordem e de Freundlich. Os parâmetros termodinâmicos indicam que a adsorção, tanto do E2 como do EE2, é um processo espontâneo a temperatura ambiente e exotérmico. A faixa de valores de Entalpia de adsorção para o E2 e EE2 (-104 a -75 kJ mol-1) indica que a adsorção na Al-MCM-41 (Si/Al = 10,5) ocorre majoritariamente via fisissorção. Este estudo apresenta conhecimentos sobre possíveis novos adsorventes sintéticos, a Al-MCM-41, de baixo custo de síntese com uma alta viabilidade para a eficiente remoção dos resíduos desses hormônios, cuja presença é crescente nos corpos aquáticos usados para abastecimento da população.
In recent decades, the presence of pharmaceutical residues, especially endocrine disruptors, in the waters of rivers, lakes, and reservoirs has drawn attention to their impacts on human health and ecosystems. These components are called emerging pollutants due to the risks they present, even at low concentrations, and the lack of legislation regarding the limits present in effluents. An endocrine disruptor acts by mimicking or simulating the body's natural hormones, potentially acting as an antagonist, altering its metabolism in vivo. Additionally, it can bind to a receptor within a cell and block the binding of the endogenous hormone. By interfering with the body's endocrine system, it produces adverse effects on development, reproduction, neurology, and immunity in humans and wildlife. In light of this, this work aims to study the performance of mesoporous silica Al-MCM-41 (Si/Al = 10.5) in the adsorption of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2). Characterization results show that the synthesized Al-MCM-41 adsorbent has an ordered hexagonal structure with a high specific surface area of around 760 m² g⁻¹. The best adsorption capacity for both E2 and EE2 occurs at pH 3.0 and reaches equilibrium after 60 minutes of contact. The Al-MCM-41 adsorbent shows excellent hormone removal performance, with qmax around 84 mg E2 g⁻¹ and 75 mg EE2 g⁻¹. Kinetic and equilibrium studies showed the best fit for the non-linear pseudo-first-order and Freundlich models. Thermodynamic parameters indicate that the adsorption of both E2 and EE2 is a spontaneous process at room temperature (ΔG° < 0) and exothermic. The range of ΔHads values for E2 and EE2 (-104 to -75 kJ mol⁻¹) indicates that adsorption on Al-MCM-41 (Si/Al = 10.5) occurs mainly via physisorption. This study provides insights into possible new synthetic adsorbents, Al-MCM-41, with low synthesis cost and high feasibility for the efficient removal of these hormone residues, whose presence is increasing in water bodies used for population supply.
In recent decades, the presence of pharmaceutical residues, especially endocrine disruptors, in the waters of rivers, lakes, and reservoirs has drawn attention to their impacts on human health and ecosystems. These components are called emerging pollutants due to the risks they present, even at low concentrations, and the lack of legislation regarding the limits present in effluents. An endocrine disruptor acts by mimicking or simulating the body's natural hormones, potentially acting as an antagonist, altering its metabolism in vivo. Additionally, it can bind to a receptor within a cell and block the binding of the endogenous hormone. By interfering with the body's endocrine system, it produces adverse effects on development, reproduction, neurology, and immunity in humans and wildlife. In light of this, this work aims to study the performance of mesoporous silica Al-MCM-41 (Si/Al = 10.5) in the adsorption of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2). Characterization results show that the synthesized Al-MCM-41 adsorbent has an ordered hexagonal structure with a high specific surface area of around 760 m² g⁻¹. The best adsorption capacity for both E2 and EE2 occurs at pH 3.0 and reaches equilibrium after 60 minutes of contact. The Al-MCM-41 adsorbent shows excellent hormone removal performance, with qmax around 84 mg E2 g⁻¹ and 75 mg EE2 g⁻¹. Kinetic and equilibrium studies showed the best fit for the non-linear pseudo-first-order and Freundlich models. Thermodynamic parameters indicate that the adsorption of both E2 and EE2 is a spontaneous process at room temperature (ΔG° < 0) and exothermic. The range of ΔHads values for E2 and EE2 (-104 to -75 kJ mol⁻¹) indicates that adsorption on Al-MCM-41 (Si/Al = 10.5) occurs mainly via physisorption. This study provides insights into possible new synthetic adsorbents, Al-MCM-41, with low synthesis cost and high feasibility for the efficient removal of these hormone residues, whose presence is increasing in water bodies used for population supply.