High voltage pulsed current in collagen realignment, synthesis, and angiogenesis after Achilles tendon partial rupture

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dc.citation.issue4
dc.citation.volume20
dc.contributor.authorRampazo, Erika P. [UNIFESP]
dc.contributor.authorLiebano, Richard E.
dc.contributor.authorPinfildi, Carlos Eduardo [UNIFESP]
dc.contributor.authorFolha, Roberta A. C. [UNIFESP]
dc.contributor.authorFerreira, Lydia M. [UNIFESP]
dc.coverageSao Carlos Sp
dc.date.accessioned2020-08-14T13:44:21Z
dc.date.available2020-08-14T13:44:21Z
dc.date.issued2016
dc.description.abstractObjective: To verify the efficacy of high voltage pulsed current in collagen realignment and synthesis and in angiogenesis after the partial rupturing of the Achilles tendon in rats. Method: Forty male Wistar rats were randomized into four groups of 10 animals each: sham, cathodic stimulation, anodic stimulation, and alternating stimulation. Their Achilles tendons were submitted to direct trauma by a free-falling metal bar. Then, the treatment was administered for six consecutive days after the injury. In the simulation group, the electrodes were positioned on the animal, but the device remained off for 30 minutes. The other groups used a frequency of 120 pps, sensory threshold, and the corresponding polarity. On the seventh day, the tendons were removed and sent for histological slide preparation for birefringence and Picrosirius Red analysis and for blood vessel quantification. Results: No significant difference was observed among the groups regarding collagen realignment (types I or III collagen) or quantity of blood vessels. Conclusion: High voltage pulsed current for six consecutive days was not effective in collagen realignment, synthesis, or angiogenesis after the partial rupturing of the Achilles tendon in rats.en
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, Dept Cirurgia Plast, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Carlos UFSCar, Dept Fisioterapia, Sao Carlos, SP, Brazil
dc.description.affiliationUNIFESP, Dept Ciencias Movimento Humano, Santos, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, Dept Cirurgia Plast, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUNIFESP, Dept Ciencias Movimento Humano, Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent312-319
dc.identifierhttp://dx.doi.org/10.1590/bjpt-rbf.2014.0167
dc.identifier.citationBrazilian Journal Of Physical Therapy. Sao Carlos Sp, v. 20, n. 4, p. 312-319, 2016.
dc.identifier.doi10.1590/bjpt-rbf.2014.0167
dc.identifier.fileWOS000383791500004.pdf
dc.identifier.issn1413-3555
dc.identifier.scieloS1413-35552016000400312
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57617
dc.identifier.wosWOS:000383791500004
dc.language.isoeng
dc.publisherAssociacao Brasileira Pesquisa Pos-Graduacao Fisioterapia-Abrapg-Ft
dc.relation.ispartofBrazilian Journal Of Physical Therapy
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectelectrical stimulationen
dc.subjecttendinopathyen
dc.subjecthealingen
dc.subjectphysical agentsen
dc.subjecttissue repairen
dc.subjectphysical therapyen
dc.titleHigh voltage pulsed current in collagen realignment, synthesis, and angiogenesis after Achilles tendon partial ruptureen
dc.typeinfo:eu-repo/semantics/article
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