Experience with the orthotopic ileal neobladder in women: a mid-term follow-up

dc.contributor.authorNesrallah, Luciano João [UNIFESP]
dc.contributor.authorAlmeida, Fernando Gonçalves [UNIFESP]
dc.contributor.authorDall'Oglio, Marcos Francisco [UNIFESP]
dc.contributor.authorNesrallah, Adriano João [UNIFESP]
dc.contributor.authorSrougi, Miguel [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionBeneficent Portuguese Hosp
dc.date.accessioned2016-01-24T12:37:49Z
dc.date.available2016-01-24T12:37:49Z
dc.date.issued2005-05-01
dc.description.abstractOBJECTIVETo report our experience with orthotopic bladder reconstruction in women, as currently the ileal orthotopic neobladder is the diversion of choice for women requiring a bladder substitute at our institution.PATIENTS and METHODSFrom February 1995 to March 2001, 29 women with muscle-invasive bladder carcinoma underwent a nerve-sparing radical cystectomy and had an orthotopic ileal neobladder reconstructed. the outcome was evaluated at 2 and 6 months and then yearly, by a clinical history, physical examination, voiding diary, stress test and estimate of functional neobladder capacity.RESULTSAll patients were followed for at least 14 months (mean 27.5); there were no major complications related to the surgery. the mean (range) neobladder capacity 2 months after surgery was 250 (190-320) mL; at 6 months it increased, remaining stable for the remaining follow-up, at 450 (350-700) mL. Four patients (14%) had nocturnal incontinence and one stress urinary incontinence, associated with using three pads per day. Three patients (10%) required catheterization for a postvoid urinary residual of > 100 mL. of the 29 patients, seven died with metastatic disease and three from causes unrelated to the reservoir or bladder cancer. Currently, 19 patients (65%) are alive and disease-free, with a mean follow-up of 35 months.CONCLUSIONOrthotopic neobladder reconstruction in women, using 40 cm of ileum, is safe and gives high continence and low urinary retention rates. Therefore, it should be advised as the first option in women with good renal function and a tumour-free bladder neck.en
dc.description.affiliationUniversidade Federal de São Paulo, EPM, Dept Urol, São Paulo, Brazil
dc.description.affiliationBeneficent Portuguese Hosp, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, EPM, Dept Urol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1045-1047
dc.identifierhttp://dx.doi.org/10.1111/j.1464-410X.2005.05463.x
dc.identifier.citationBju International. Oxford: Blackwell Publishing Ltd, v. 95, n. 7, p. 1045-1047, 2005.
dc.identifier.doi10.1111/j.1464-410X.2005.05463.x
dc.identifier.issn1464-4096
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/28264
dc.identifier.wosWOS:000228397500028
dc.language.isoeng
dc.publisherBlackwell Publishing Ltd
dc.relation.ispartofBju International
dc.rightsAcesso aberto
dc.subjectbladderen
dc.subjectcystectomyen
dc.subjecturinary diversionen
dc.subjectcontinenten
dc.subjectwomenen
dc.titleExperience with the orthotopic ileal neobladder in women: a mid-term follow-upen
dc.typeArtigo
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