Serum Antioxidant Associations with Metabolic Characteristics in Metabolically Healthy and Unhealthy Adolescents with Severe Obesity: An Observational Study

Página do item simplificado
dc.citation.issue2
dc.citation.volume10
dc.contributor.authorStenzel, Ana Paula
dc.contributor.authorCarvalho, Roberta
dc.contributor.authorJesus, Patricia
dc.contributor.authorBull, Aline
dc.contributor.authorPereira, Silvia
dc.contributor.authorSaboya, Carlos [UNIFESP]
dc.contributor.authorRamalho, Andrea
dc.coverageBasel
dc.date.accessioned2020-07-08T13:09:44Z
dc.date.available2020-07-08T13:09:44Z
dc.date.issued2018
dc.description.abstractConsidering the inadequacy of some antioxidant nutrients in severely obese adolescents, this study aimed to assess the relationship between antioxidant micronutrients status and metabolic syndrome components in metabolically healthy obesity (MHO) and unhealthy obesity (MUO). We performed an observational study in severely obese adolescents (body mass index > 99th percentile) and they were classified into MHO or MUO, according to the criteria adapted for adolescents. Anthropometric, biochemical, and clinical variables were analyzed to characterize the sample of adolescents. The serum antioxidant nutrients assessed were retinol, beta-carotene, Vitamin E, Vitamin C, zinc and selenium. A total of 60 adolescents aged 17.31 +/- 1.34 years were enrolled. MHO was identified in 23.3% of adolescents. The MHO group showed lower frequency of non-alcoholic fatty liver disease (14.3% vs. 78.3%, p < 0.001) when compared to MUO. A correlation was found between retinol and beta-carotene concentrations with glycemia (r = -0.372en
dc.description.abstractp = 0.011 and r = -0.314en
dc.description.abstractp = 0.034, respectively) and between Vitamin E with waist circumference (r = -0.306en
dc.description.abstractp = 0.038) in the MUO group. The current study shows that some antioxidant nutrients status, specifically retinol, beta-carotene, and Vitamin E, are negatively associated with metabolic alterations in MUO. Further studies are necessary to determine the existing differences in the serum antioxidant profile of metabolically healthy and unhealthy obese adolescents.en
dc.description.affiliationFed Univ Rio de Janeiro UFRJ, Sch Med, BR-21941902 Rio De Janeiro, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Ctr Res Micronutrients NPqM, Inst Nutr Josue de Castro, BR-21941902 Rio de Janeiro, Brazil
dc.description.affiliationMultidisciplinary Ctr Bariatr & Metab Surg, BR-22280020 Rio De Janeiro, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Dept Social & Appl Nutr, Inst Nutr, BR-21941902 Rio de Janeiro, Brazil
dc.description.affiliationFed Univ Sao Paulo UNIFESP, Escola Paulista Med, BR-04021001 Sao Paulo, Brazil
dc.description.affiliationUnifespFed Univ Sao Paulo UNIFESP, Escola Paulista Med, BR-04021001 Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ) (Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro)
dc.format.extent-
dc.identifierhttp://dx.doi.org/10.3390/nu10020150
dc.identifier.citationNutrients. Basel, v. 10, n. 2, p. -, 2018.
dc.identifier.doi10.3390/nu10020150
dc.identifier.fileWOS000427540000040.pdf
dc.identifier.issn2072-6643
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54170
dc.identifier.wosWOS:000427540000040
dc.language.isoeng
dc.publisherMdpi
dc.relation.ispartofNutrients
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectobesityen
dc.subjectadolescentsen
dc.subjectMetabolically Healthy Obesityen
dc.subjectantioxidantsen
dc.titleSerum Antioxidant Associations with Metabolic Characteristics in Metabolically Healthy and Unhealthy Adolescents with Severe Obesity: An Observational Studyen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
WOS000427540000040.pdf
Tamanho:
423.48 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Coleções
EPM - Artigos