Relationship between Retinopathy Severity, Visual Impairment and Depression in Persons with Long-term Type 1 Diabetes

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dc.contributor.authorHirai, Flavio E. [UNIFESP]
dc.contributor.authorTielsch, James M.
dc.contributor.authorKlein, Barbara E. K.
dc.contributor.authorKlein, Ronald
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionJohns Hopkins Univ
dc.contributor.institutionUniv Wisconsin
dc.date.accessioned2016-01-24T14:27:33Z
dc.date.available2016-01-24T14:27:33Z
dc.date.issued2012-08-01
dc.description.abstractPurpose: Our aim was to investigate the proportion of individuals with depression and its association with diabetic retinopathy and visual impairment in a cohort with 25 or more years of type 1 diabetes.Methods: This was a cross-sectional analysis at the 25-year follow-up of the population-based cohort of the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Examinations followed standardized protocols and included clinical and ophthalmic evaluations and questionnaires to assess current and past medical history, use of medications, and cigarette smoking. the Center for Epidemiologic Studies Depression Scale (CES-D) was administered to all participants. Depression was defined as use of antidepressant or CES-D score >= 16.Results: A total of 484 individuals were included in the analysis. the proportion of depression was 37.8% (95% confidence interval 33.4-42.3%). A higher proportion of individuals with depression was observed among those with more severe diabetic retinopathy and visual impairment. However these associations were not statistically significant while controlling for other factors in the multivariable analyses.Conclusions: Diabetic retinopathy severity and visual acuity in persons with long duration of type 1 diabetes were not cross-sectionally associated with depression in this cohort.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Ophthalmol, BR-04023062 São Paulo, Brazil
dc.description.affiliationJohns Hopkins Univ, Dept Epidemiol, Bloomberg Sch Publ Hlth, Baltimore, MD USA
dc.description.affiliationJohns Hopkins Univ, Dept Int Hlth, Bloomberg Sch Publ Hlth, Baltimore, MD USA
dc.description.affiliationUniv Wisconsin, Dept Ophthalmol & Visual Sci, Madison, WI USA
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Ophthalmol, BR-04023062 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipNational Institutes of Health
dc.description.sponsorshipAmerican Diabetes Association, Alexandria, VA
dc.description.sponsorshipResearch to Prevent Blindness, New York, NY
dc.description.sponsorshipNational Eye Institute
dc.description.sponsorshipIDNational Institutes of Health: EY016379
dc.format.extent196-203
dc.identifierhttp://dx.doi.org/10.3109/09286586.2012.692006
dc.identifier.citationOphthalmic Epidemiology. London: Informa Healthcare, v. 19, n. 4, p. 196-203, 2012.
dc.identifier.doi10.3109/09286586.2012.692006
dc.identifier.issn0928-6586
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35164
dc.identifier.wosWOS:000306191300004
dc.language.isoeng
dc.publisherInforma Healthcare
dc.relation.ispartofOphthalmic Epidemiology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf
dc.subjectDiabetic retinopathyen
dc.subjectVisual impairmenten
dc.subjectDepressionen
dc.subjectType 1 diabetesen
dc.subjectEpidemiologyen
dc.titleRelationship between Retinopathy Severity, Visual Impairment and Depression in Persons with Long-term Type 1 Diabetesen
dc.typeinfo:eu-repo/semantics/article
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