Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties

dc.citation.volume649
dc.contributor.authorSandrino, B.
dc.contributor.authorWrobel, E. C.
dc.contributor.authorNobre, T. M.
dc.contributor.authorCaseli, Luciano [UNIFESP]
dc.contributor.authorLazaro, S. R.
dc.contributor.authorJunior, A. C.
dc.contributor.authorGarcia, J. R.
dc.contributor.authorOliveira Jr., O. N.
dc.contributor.authorWohnrath, K.
dc.coverageAmsterdam
dc.date.accessioned2020-07-22T13:23:15Z
dc.date.available2020-07-22T13:23:15Z
dc.date.issued2016
dc.description.abstractWe report on the interaction between mer-[RuCl3(dppb)(VPy)] (dppb = 1,4-bis(diphenylphosphine)-butane and VPy=4-vinylpyridine) (RuVPy) and dipalmitoyl phosphatidyl serine (DPPS), in Langmuir and Langmuir-Blodgett (LB) films. Interaction of RuVPy with DPPS, which predominates in cancer cell membranes, should be weaker than for other phospholipids since RuVPy is less toxic to cancer cells than to healthy cells. Incorporation of RuVPy induced smaller changes in electrochemical properties of LB films of DPPS than for other phospholipids, but the same did not apply to surface pressure isotherms. This calls for caution in establishing correlations between effects from a single property and phenomena on cell membranes. (C) 2014 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniv Estadual Ponta Grossa, Appl Chem Program, BR-84035900 Ponta Grossa, PR, Brazil
dc.description.affiliationUniv Sao Paulo, Sao Carlos Inst Phys, BR-13560970 Sao Carlos, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Exact Sci, BR-09972270 Diadema, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Exact Sci, BR-09972270 Diadema, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFAPESP (Brazil)
dc.description.sponsorshipCNPq (Brazil)
dc.description.sponsorshipCAPES (Brazil)
dc.description.sponsorshipnBioNet (Brazil)
dc.format.extent29-36
dc.identifierhttp://dx.doi.org/10.1016/j.cplett.2016.02.023
dc.identifier.citationChemical Physics Letters. Amsterdam, v. 649, p. 29-36, 2016.
dc.identifier.doi10.1016/j.cplett.2016.02.023
dc.identifier.issn0009-2614
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56127
dc.identifier.wosWOS:000373274100006
dc.language.isoeng
dc.publisherElsevier Science Bv
dc.relation.ispartofChemical Physics Letters
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleInteraction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical propertiesen
dc.typeinfo:eu-repo/semantics/article
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