Efeitos em curto prazo da aplicação de aloxana para indução de diabetes em ratos Wistar

dc.contributor.authorLeme, Jose Alexandre Curiacos de Almeida
dc.contributor.authorCastellar, Alexandre
dc.contributor.authorRemedio, Rafael Neodini
dc.contributor.authorBarbosa, Rodrigo Avelaira
dc.contributor.authorMoura, Leandro Pereira de
dc.contributor.authorDalia, Rodrigo Augusto
dc.contributor.authorGomes, Ricardo José [UNIFESP]
dc.contributor.authorCaetano, Flavio Henrique
dc.contributor.authorMello, Maria Alice Rostom de
dc.contributor.authorLuciano, Eliete
dc.contributor.institutionUniv Estadual Paulista
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T14:04:27Z
dc.date.available2018-06-15T14:04:27Z
dc.date.issued2010-05-01
dc.description.abstractThe present study aimed to verify action of alloxan in metabolic and immune parameters after 24 and 192 hours of the injection in Wistar rats. Thus, eight rats were fasted and received monohidrated alloxan Sigma (32 mg/kg body weight) via endovenous. Glycemia and trglyceridemia analyzes were performed before and 192 hours after alloxan application. After 24 hours, alloxan application increased water intake and decreased body mass, food intake and leucocytes counting. 192 hours after alloxan application, there was a recuperation in food intake and leucocytes counting. On the other hand, in this period there was an increase of glycemia and water intake and reduction of body mass. These results indicate that some of diabetic signs caused by alloxan occur in short-term after drug administration.en
dc.description.affiliationUniv Estadual Paulista, Dept Educ Fis, Sao Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Dept Biol, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo Baixada Santista, Sao Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Dept Ciencias Biol, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo Baixada Santista, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent442-447
dc.identifierhttps://www.seer.ufu.br/index.php/biosciencejournal/article/view/7094/4858
dc.identifier.citationBioscience Journal. Uberlandia: Univ Federal Uberlandia, v. 26, n. 3, p. 442-447, 2010.
dc.identifier.fileWOS000282056200015.pdf
dc.identifier.issn1516-3725
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/42839
dc.identifier.wosWOS:000282056200015
dc.language.isopor
dc.publisherUniv Federal Uberlandia
dc.relation.ispartofBioscience Journal
dc.rightsAcesso aberto
dc.subjectAlloxanen
dc.subjectDiabetesen
dc.subjectMetabolismen
dc.subjectImmune Systemen
dc.titleEfeitos em curto prazo da aplicação de aloxana para indução de diabetes em ratos Wistarpt
dc.title.alternativeEffects in short-term of alloxan application to diabetes induction in Wistar ratsen
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