Low-grade sarcoma in classical seminoma - the first case reported

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dc.contributor.authorPetersson, Fredrik
dc.contributor.authorMichal, Michal
dc.contributor.authorGrossmann, Petr
dc.contributor.authorFranco, Marcello Fabiano de [UNIFESP]
dc.contributor.authorZamecnik, Michal
dc.contributor.authorHes, Ondrej
dc.contributor.institutionNatl Univ Hlth Syst
dc.contributor.institutionUniversidade Estadual de Maringá (UEM)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionBiopticka Lab Sro
dc.date.accessioned2018-06-15T17:44:18Z
dc.date.available2018-06-15T17:44:18Z
dc.date.issued2010-01-01
dc.description.abstractA 30-year-old male with no previous history of neoplastic disease presented with a 5 cm large testicular tumor. Routine histopathological examination and immunohistochemical investigation showed a classical seminoma with a contiguous 8 mm large nodule. The nodule was separated from the tunica albuginea by tubuli semi-niferi showing intratesticular germ cell neoplasi not otherwise specified (NOS). The nodule was composed of spindle cells with low-grade nuclear atypia, nuclear and cytoplasmic S100 protein immunoreactivity in 15% of the cells and a proliferative activity of up to 20%. No other germ cell tumor components were found. To the best of our knowledge, we herein present the first tumor of a pure classical seminoma with an associated low-grade sarcomatous component.en
dc.description.affiliationNatl Univ Hlth Syst, Dept Pathol, Singapore 119074, Singapore
dc.description.affiliationCharles Univ Prague, Med Fac Hosp, Sikls Dept Pathol, Plzen, Czech Republic
dc.description.affiliationFed Univ Sao Paolo, EPM UNIFESP, Dept Pathol, Sao Paulo, Brazil
dc.description.affiliationBiopticka Lab Sro, Plzen, Czech Republic
dc.description.affiliationUnifespFed Univ Sao Paolo, EPM UNIFESP, Dept Pathol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent203-209
dc.identifierhttp://www.ijcep.com/907001A.html
dc.identifier.citationInternational Journal Of Clinical And Experimental Pathology. Madison: E-century Publishing Corp, v. 3, n. 2, p. 203-209, 2010.
dc.identifier.fileWOS000293505800009.pdf
dc.identifier.issn1936-2625
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/44029
dc.identifier.wosWOS:000293505800009
dc.language.isoeng
dc.publisherE-century Publishing Corp
dc.relation.ispartofInternational Journal Of Clinical And Experimental Pathology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTestisen
dc.subjectclassical seminomaen
dc.subjectsarcomaen
dc.titleLow-grade sarcoma in classical seminoma - the first case reporteden
dc.typeinfo:eu-repo/semantics/article
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