Clinical-histopathological correlation in a case of Coats' disease

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dc.contributor.authorFernandes, Bruno F. [UNIFESP]
dc.contributor.authorOdashiro, Alexandre N. [UNIFESP]
dc.contributor.authorMaloney, Shawn
dc.contributor.authorZajdenweber, Moyses E.
dc.contributor.authorLopes, Andressa G.
dc.contributor.authorBurnier, Miguel N. [UNIFESP]
dc.contributor.institutionMcGill Univ
dc.contributor.institutionHenry C Witelson Ocular Pathol Lab
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionHosp Servidores Estado
dc.date.accessioned2016-01-24T12:38:14Z
dc.date.available2016-01-24T12:38:14Z
dc.date.issued2006-01-01
dc.description.abstractBackground: Coats' disease is a non-hereditary ocular disease, with no systemic manifestation, first described by Coats in 1908. It occurs more commonly in children and has a clear male predominance. Most patients present clinically with unilateral decreased vision, strabismus or leukocoria. the most important differential diagnosis is unilateral retinoblastoma, which occurs in the same age group and has some overlapping clinical manifestations.Case presentation: A 4 year-old girl presented with a blind and painful right eye. Ocular examination revealed neovascular glaucoma, cataract and posterior synechiae. Although viewing of the fundus was impossible, computed tomography disclosed total exsudative retinal detachment in the affected eye. the eye was enucleated and subsequent histopathological evaluation confirmed the diagnosis of Coats' disease.Conclusion: General pathologists usually do not have the opportunity to receive and study specimens from patients with Coats' disease. Coats' disease is one of the most important differential diagnoses of retinoblastoma. Therefore, It is crucial for the pathologist to be familiar with the histopathological features of the former, and distinguish it from the latter.en
dc.description.affiliationMcGill Univ, Ctr Hlth, Dept Ophthalmol & Pathol, Montreal, PQ, Canada
dc.description.affiliationHenry C Witelson Ocular Pathol Lab, Montreal, PQ, Canada
dc.description.affiliationUniversidade Federal de São Paulo, EPM, Dept Ophthalmol, UNIFESP, São Paulo, Brazil
dc.description.affiliationHosp Servidores Estado, Dept Ophthalmol, Rio de Janeiro, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, EPM, Dept Ophthalmol, UNIFESP, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent4
dc.identifierhttp://dx.doi.org/10.1186/1746-1596-1-24
dc.identifier.citationDiagnostic Pathology. London: Biomed Central Ltd, v. 1, 4 p., 2006.
dc.identifier.doi10.1186/1746-1596-1-24
dc.identifier.fileWOS000205613100024.pdf
dc.identifier.issn1746-1596
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/28616
dc.identifier.wosWOS:000205613100024
dc.language.isoeng
dc.publisherBiomed Central Ltd
dc.relation.ispartofDiagnostic Pathology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleClinical-histopathological correlation in a case of Coats' diseaseen
dc.typeinfo:eu-repo/semantics/article
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