Pediatric corneal transplants

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dc.contributor.authorTrief, Danielle
dc.contributor.authorMarquezan, Maria C. [UNIFESP]
dc.contributor.authorRapuano, Christopher J.
dc.contributor.authorPrescott, Christina R.
dc.date.accessioned2019-08-19T11:49:36Z
dc.date.available2019-08-19T11:49:36Z
dc.date.issued2017
dc.description.abstractPurpose of reviewPediatric keratoplasty poses unique challenges in clinical and surgical management. However, successful transplantation can afford a child vision in an otherwise poorly seeing eye. This review will provide an update on recent advances in pediatric keratoplasty.Recent findingsAlthough children who receive corneal transplants remain at increased risk of rejection, infection, and graft dehiscence compared with adult corneal transplant recipients, new surgical techniques, and advances in clinical management have led to better outcomes. Surgical modifications in penetrating keratoplasty (PKP) offer increased stabilization of the delicate pediatric eye. Lamellar surgery, including endothelial keratoplasty and deep anterior lamellar keratoplasty, can target specific diseased tissue in children with potentially fewer complications. The keratoprosthesis can be used successfully in children when the chance of success with PKP is especially low.SummaryAs our knowledge of prognostic indicators and surgical techniques continues to grow, we can offer children safer and more targeted surgeries for some of the most challenging corneal diseases. Ultimately, successful transplantation with long-term graft survival can be obtained by a multidisciplinary approach, with care across ophthalmic specialties, and a commitment to long-term follow-up by the patient's family.en
dc.description.affiliationColumbia Univ, Med Ctr, Dept Ophthalmol, New York, NY 10027 USA
dc.description.affiliationUniv Fed São Paulo, UNIFESP, Dept Ophthalmol & Visual Sci, Paulista Sch Med, São Paulo, SP, Brazil
dc.description.affiliationWills Eye Hosp & Res Inst, Cornea Serv, Philadelphia, PA USA
dc.description.affiliationJohns Hopkins Univ, Wilmer Eye Inst, Baltimore, MD USA
dc.description.affiliationUnifespUniv Fed São Paulo, UNIFESP, Dept Ophthalmol & Visual Sci, Paulista Sch Med, São Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent477-484
dc.identifierhttp://dx.doi.org/10.1097/ICU.0000000000000393
dc.identifier.citationCurrent Opinion In Ophthalmology. Philadelphia, v. 28, n. 5, p. 477-484, 2017.
dc.identifier.doi10.1097/ICU.0000000000000393
dc.identifier.issn1040-8738
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/51357
dc.identifier.wosWOS:000407837000012
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectdeep anterior lamellar keratoplastyen
dc.subjectDescemet's stripping automated endothelial keratoplastyen
dc.subjectDescemet's stripping endothelial keratoplastyen
dc.subjectkeratoprosthesisen
dc.subjectpediatric keratoplastyen
dc.subjectPKPen
dc.titlePediatric corneal transplantsen
dc.typeinfo:eu-repo/semantics/review
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