Sacroiliac Joint Magnetic Resonance Imaging in Asymptomatic Patients with Recurrent Acute Anterior Uveitis: A Proof-of-concept Study

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dc.citation.issue12
dc.citation.volume44
dc.contributor.authorOliveira, Thauana L. [UNIFESP]
dc.contributor.authorMaksymowych, Walter P.
dc.contributor.authorLambert, Robert G. W.
dc.contributor.authorMuccioli, Cristina [UNIFESP]
dc.contributor.authorFernandes, Artur R. C. [UNIFESP]
dc.contributor.authorPinheiro, Marcelo M. [UNIFESP]
dc.coverageToronto
dc.date.accessioned2020-09-01T13:21:10Z
dc.date.available2020-09-01T13:21:10Z
dc.date.issued2017
dc.description.abstractObjective. Our aim was to quantify bone marrow edema (BME) and/or structural lesions in the sacroiliac joints (SIJ) of patients with recurrent acute anterior uveitis (rAAU) with or without back pain, to evaluate the frequency of axial (axSpA) and peripheral spondyloarthritis (pSpA) and to establish which criterion for magnetic resonance imaging (MRI) positivity best reflected the global assessment of SIJ MRI. Methods. A total of 50 patients with rAAU without prior rheumatologic diagnosis were included in our cross-sectional study, and these patients were compared to 21 healthy volunteers. SIJ MRI scans were read by 2 rheumatologists according to the Spondyloarthritis Research Consortium of Canada (SPARCC/MORPHO) protocol. Discrepant cases were adjudicated by a radiologist. Results. Patients with rAAU were diagnosed with axSpA (Group 1, n = 20, 40%) and nonspecific back pain (Group 2, n = 6, 12%), or as being asymptomatic (Group 3, n = 24, 48%). Group 3 results showed 9 patients (37.5%) had SIJ MRI and/or were radiography-positive for axSpA (5 MRI and radiograph, 1 MRI, 3 radiograph). SIJ MRI scans that were compatible with SpA in groups 1 (n = 12) and 3 (n = 6) were similar in acute and structural lesions that were analyzed according to SPARCC/MORPHO. The best sensitivity/specificity criterion for defining a positive global MRI assessment was a BME score = 3 (88%/94%). Conclusion. This is the first study evaluating SIJ MRI in patients with rAAU without back symptoms, showing positive findings for sacroiliitis. Moreover, a BME score >= 3 had better performance to define an SIJ MRI as positive for axSpA.en
dc.description.affiliationFed Univ Sao Paulo UNIFESP EPM, Dept Ophthalmol, Div Rheumatol, Sao Paulo, Brazil
dc.description.affiliationFed Univ Sao Paulo UNIFESP EPM, Dept Radiol & Diagnost Imaging, Sao Paulo, Brazil
dc.description.affiliationUniv Alberta, Dept Med, Edmonton, AB, Canada
dc.description.affiliationUniv Alberta, Dept Radiol & Diagnost Imaging, Edmonton, AB, Canada
dc.description.affiliationUNIFESP EPM, Div Rheumatol, Sao Paulo, Brazil
dc.description.affiliationUNIFESP EPM, Dept Ophthalmol, Sao Paulo, Brazil
dc.description.affiliationUNIFESP EPM, Dept Radiol & Diagnost Imaging, Sao Paulo, Brazil
dc.description.affiliationUNIFESP EPM, Div Rheumatol, Sao Paulo, Brazil
dc.description.affiliationUnifespFed Univ Sao Paulo UNIFESP EPM, Dept Ophthalmol, Div Rheumatol, Sao Paulo, Brazil
dc.description.affiliationUnifespFed Univ Sao Paulo UNIFESP EPM, Dept Radiol & Diagnost Imaging, Sao Paulo, Brazil
dc.description.affiliationUnifespUNIFESP EPM, Div Rheumatol, Sao Paulo, Brazil
dc.description.affiliationUnifespUNIFESP EPM, Dept Ophthalmol, Sao Paulo, Brazil
dc.description.affiliationUnifespUNIFESP EPM, Dept Radiol & Diagnost Imaging, Sao Paulo, Brazil
dc.description.affiliationUnifespUNIFESP EPM, Div Rheumatol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1833-1840
dc.identifierhttp://dx.doi.org/10.3899/jrheum.170036
dc.identifier.citationJournal Of Rheumatology. Toronto, v. 44, n. 12, p. 1833-1840, 2017.
dc.identifier.doi10.3899/jrheum.170036
dc.identifier.issn0315-162X
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/58103
dc.identifier.wosWOS:000416883500011
dc.language.isoeng
dc.publisherJ Rheumatol Publ Co
dc.relation.ispartofJournal Of Rheumatology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSPONDYLOARTHRITISen
dc.subjectMAGNETIC RESONANCE IMAGINGen
dc.subjectSACROILIAC JOINTSen
dc.titleSacroiliac Joint Magnetic Resonance Imaging in Asymptomatic Patients with Recurrent Acute Anterior Uveitis: A Proof-of-concept Studyen
dc.typeinfo:eu-repo/semantics/article
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