Maternal BMI and preterm birth: A systematic review of the literature with meta-analysis
Data
2009-01-01
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Objectives. To examine the association between high prepregnancy maternal body mass index (BMI) and the risk of preterm birth (PTB).Methods. A systematic review of the literature. We included cohorts and case-control studies published since 1968 that examined the association between BMI and PTB of all types, spontaneous (s), elective and with ruptured membranes (PPROM) in three gestational age categories: general (<37 weeks), moderate (32-36 weeks) and very (<32 weeks) PTB.Results. 20,401 citations were screened and 39 studies (1,788,633 women) were included. Preobese (BMI, 25-29.9) and obese I (BMI, 30-34.9) women have a reduced risk for sPTB: AOR - 0.85 (95% CI: 0.80-0.92) and 0.83 (95% CI: 0.75-0.92), respectively. Their risk for moderate PTB was 1.20 (95% CI: 1.04-1.38) and 1.60 (95% CI: 1.32-1.94), respectively. Obese II women (BMI, 35-40) have an increased risk for PTB in general (AOR = 1.33, 95% CI: 1.12-1.57) moderate (AOR - 2.43, 95% CI: 1.46-4.05) and very PTB (AOR - 1.96, 95% CI: 1.66-2.31). Obese III women (BMI > 40) have an even higher risk for very PTB (AOR = 2.27, 95% CI: 1.76-2.94). High BMI does not modify the risk for PPROM and increases the risk for elective PTB.Conclusions. High maternal BMI may have different effects on different types of PTB.
Descrição
Citação
Journal of Maternal-fetal & Neonatal Medicine. Abingdon: Taylor & Francis Ltd, v. 22, n. 11, p. 957-970, 2009.