Choroidal thickness in retinal pigment epithelial tear as measured by spectral domain optical coherence tomography

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dc.contributor.authorBhavsar, Kavita V.
dc.contributor.authorBranchini, Lauren
dc.contributor.authorShah, Heeral
dc.contributor.authorRegatieri, Caio Vinicius Saito [UNIFESP]
dc.contributor.authorDuker, Jay S.
dc.contributor.institutionTufts Med Ctr
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-18T11:35:38Z
dc.date.available2018-06-18T11:35:38Z
dc.date.issued2014-01-01
dc.description.abstractPurpose: To evaluate the choroidal thickness with spectral domain optical coherence tomography in subjects with retinal pigment epithelial (RPE) tear compared with the choroidal thickness of their fellow eye.Methods: For this cross-sectional investigation, seven eyes of seven patients with neovascular age-related macular degeneration and RPE tear in one eye imaged with spectral domain optical coherence tomography were identified. Choroidal thickness was measured from the posterior edge of the retinal pigment epithelium to the choroid/sclera junction at 500 mu m intervals up to 2,500 mu m temporal and nasal to the fovea in both the eye with the RPE tear and the eye with intact RPE. All measurements were performed by two independent observers and averaged for the purpose of the analysis. Measurements were compared using paired t-test.Results: The average age of patients was 79 years (range, 66-88 years). All subjects had dome-shaped pigment epithelial detachments before RPE tear and no dome-shaped pigment epithelial detachments in the unaffected eye. Average subfoveal choroidal thickness in the eye with the RPE tear was 154.9 +/- 10.1 mu m. Average subfoveal choroidal thickness in the eye with intact RPE was 212.9 +/- 10.6 mu m (P = 0.035).Conclusion: There is a significant decrease in subfoveal choroidal thickness in the subjects with RPE tear compared with their fellow eye with intact RPE. It is unclear if this thinning is a consequence of or precedes the RPE tear. Further studies are necessary to prospectively follow choroidal thickness in subjects with dome-shaped pigment epithelial detachments.en
dc.description.affiliationTufts Med Ctr, New England Eye Ctr, Boston, MA 02111 USA
dc.description.affiliationUniv Fed Sao Paulo, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipResearch to Prevent Blindness
dc.description.sponsorshipTufts University School of Medicine, National Institutes of Health
dc.description.sponsorshipMassachusetts Lions Eye Research Fund
dc.description.sponsorshipCarl Zeiss Meditech, Inc
dc.description.sponsorshipOptovue, Inc.
dc.description.sponsorshipIDTufts University School of Medicine, National Institutes of Health: RO1-EY11289-23
dc.description.sponsorshipIDTufts University School of Medicine, National Institutes of Health: R01-EY13178-07
dc.description.sponsorshipIDTufts University School of Medicine, National Institutes of Health: R01-EY013516-07
dc.format.extent63-68
dc.identifierhttp://dx.doi.org/10.1097/IAE.0b013e318297a061
dc.identifier.citationRetina-the Journal Of Retinal And Vitreous Diseases. Philadelphia: Lippincott Williams & Wilkins, v. 34, n. 1, p. 63-68, 2014.
dc.identifier.doi10.1097/IAE.0b013e318297a061
dc.identifier.issn0275-004X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/45225
dc.identifier.wosWOS:000336958700011
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofRetina-the Journal Of Retinal And Vitreous Diseases
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectchoroidal thicknessen
dc.subjectretinal pigment epithelial tearen
dc.subjectspectral domain optical coherence tomographyen
dc.titleChoroidal thickness in retinal pigment epithelial tear as measured by spectral domain optical coherence tomographyen
dc.typeinfo:eu-repo/semantics/article
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