Intestinal absorption of iron and calcium from soy and cow's milk-based infant formulas in weanling rats pups

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dc.citation.issue1
dc.citation.volume30
dc.contributor.authorCorreia Silva, Maisa de Lima [UNIFESP]
dc.contributor.authorSperidião, Patrícia da Graça Leite [UNIFESP]
dc.contributor.authorMarciano, Renata [UNIFESP]
dc.contributor.authorAmancio, Olga Maria Silverio [UNIFESP]
dc.contributor.authorMorais, Tania Beninga de [UNIFESP]
dc.contributor.authorMorais, Mauro Batista de [UNIFESP]
dc.coverageCampinas
dc.date.accessioned2020-07-31T12:46:52Z
dc.date.available2020-07-31T12:46:52Z
dc.date.issued2017
dc.description.abstractObjective This study aimed to compare the intestinal absorption of iron and calcium between soy-based and cow's milk- based infant formulas in weanling rats. Methods Twenty male Wistar rats, twenty-one days old on the first day of weaning, were used in this experiment, divided in two Groups, one Group was fed soy protein-based infant formula the other, cow's milk protein-based infant formula. During the study period (ten consecutive days) the animals received food and water ad libitum. Hematocrit and hemoglobin were evaluated on the first, fifth, and tenth days by the Wintrobe and cyanomethemoglobin methods. Feces and urine were collected, beginning on the fifth day, for three consecutive days. On the tenth day, hepatic iron content was also analyzed. Hepatic iron as well as fecal and urinary iron and calcium analyses were performed using an atomic absorption spectrophotometer. At thirty-one days of age, the animals were anesthetized with ketamine and xylazine and sacrificed by exsanguination via the vena cava. Results The final concentration of hemoglobin in the group soy-based infant formula and milk-based infant formula were: 10.3 +/- 1.3g/dL and 10.9 +/- 1.0g/dL (p=0.310). The apparent absorption of iron and calcium, in that order, were: 73.4 +/- 10.2% and 70.2 +/- 9.5%en
dc.description.abstract97.2 +/- 0.7% and 97.6 +/- 1.0% (p=0.501en
dc.description.abstractp=0.290). The apparent calcium retention was: 88.4%+/- 2.2 and 88.6 +/- 2.6%(p=0.848). Hepatic iron content was: 522.0 +/- 121.1mg/g and 527.8 +/- 80.5mg/g (p=0.907). Conclusion Intestinal iron and calcium absorption from soy-based infant formula is similar to that from milk-based infant formula in weanling rats.en
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Dept Pediat, R Coronel Lisboa,826,Vila Clementino, BR-04020041 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Lab Bromotol & Microbiol Alimentos, BR-04020041 Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Pediatria. R. Coronel Lisboa, 826, Vila Clementino, 04020-041, São Paulo, SP, Brasil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista de Medicina, Laboratório de Bromotologia e Microbiologia de Alimentos. São Paulo, SP, Brasil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent13-22
dc.identifierhttp://dx.doi.org/10.1590/1678-98652017000100002
dc.identifier.citationRevista De Nutricao-Brazilian Journal Of Nutrition. Campinas, v. 30, n. 1, p. 13-22, 2017.
dc.identifier.doi10.1590/1678-98652017000100002
dc.identifier.fileS1415-52732017000100013.pdf
dc.identifier.issn1415-5273
dc.identifier.scieloS1415-52732017000100013
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56422
dc.identifier.wosWOS:000396350700002
dc.language.isoeng
dc.publisherPontificia Universidade Catolica Campinas
dc.relation.ispartofRevista De Nutricao-Brazilian Journal Of Nutrition
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCalciumen
dc.subjectIntestinal absorptionen
dc.subjectIronen
dc.subjectMilk proteinsen
dc.subjectSoy proteinsen
dc.titleIntestinal absorption of iron and calcium from soy and cow's milk-based infant formulas in weanling rats pupsen
dc.typeinfo:eu-repo/semantics/article
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