Risk factors associated with wheezing in infants

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dc.contributor.authorMoraes, Lillian Sanchez Lacerda
dc.contributor.authorTakano, Olga A.
dc.contributor.authorMallol, Javier
dc.contributor.authorSole, Dirceu [UNIFESP]
dc.contributor.institutionUniv Fed Mato Grosso
dc.contributor.institutionUniv Santiago
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:34:36Z
dc.date.available2016-01-24T14:34:36Z
dc.date.issued2013-11-01
dc.description.abstractObjective: to identify possible risk factors associated with wheezing in infants (12-15 months-old) in the state of Mato Grosso, Brazil.Methods: this was a cross-sectional study performed by applying a standardized written questionnaire from the international study on wheezing in infants (Estudio Internacional de Sibilancia en Lactantes - EISL), phase 3. Parents and/or guardians of infants were interviewed at primary health care clinics or at home from August of 2009 to November of 2010. Factors associated to wheezing were studied using bivariate and multivariate analysis (using the Statistical Package for Social Sciences [SPSS] v.18.0), and expressed as odds ratios (OR) and 95% confidence intervals (95% CI).Results: the written questionnaire was answered by 1,060 parents and/or guardians. the risk factors for wheezing were: history of asthma in the family [mother (OR = 1.62; 95% CI = 1.07-2.43); father (OR = 1.98; 95% CI = 1.22-3.23); siblings (OR = 2.13; 95% CI = 1.18-3.87)]; history of previous pneumonia (OR = 10.80; 95% CI = 4.52-25.77); having had more than six upper respiratory tract infections (URTIs) (OR = 2.95; 95% CI = 2.11-4.14); having had first URTI before the third month of life (OR = 1.50; 95% CI = 1.04-2.17); living in a moderately polluted area (OR = 1.59; 95% CI = 1.08-2.33); paracetamol use for URTI (OR = 2.13; 95% CI = 1.54-2.95); and antibiotic use for skin infection (OR = 2.29; 95% CI = 1.18-4.46).Conclusions: the study of risk factors for wheezing in the first year of life is important to help physicians identify young children at high risk of developing asthma and to improve public health prevention strategies in order to reduce the morbidity of wheezing in childhood. (C) 2013 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.en
dc.description.affiliationUniv Fed Mato Grosso, Dept Pediat, Cuiaba, MT, Brazil
dc.description.affiliationUniv Santiago, Hosp CRS El Pino, Santiago, Chile
dc.description.affiliationUniversidade Federal de São Paulo, Dept Pediat, Escola Paulista Med, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Pediat, Escola Paulista Med, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent559-566
dc.identifierhttp://dx.doi.org/10.1016/j.jped.2013.04.004
dc.identifier.citationJornal de Pediatria. Rio de Janeiro, Rj: Soc Brasil Pediatria, v. 89, n. 6, p. 559-566, 2013.
dc.identifier.doi10.1016/j.jped.2013.04.004
dc.identifier.fileS0021-75572013000600008.pdf
dc.identifier.issn0021-7557
dc.identifier.scieloS0021-75572013000600008
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/36893
dc.identifier.wosWOS:000328910100008
dc.language.isopor
dc.publisherSoc Brasil Pediatria
dc.relation.ispartofJornal de Pediatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectInfanten
dc.subjectWheezingen
dc.subjectAsthmaen
dc.subjectRisk factorsen
dc.titleRisk factors associated with wheezing in infantsen
dc.typeinfo:eu-repo/semantics/article
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