Sleep deprivation alters phosphorylated CREB levels in the amygdala: Relationship with performance in a fear conditioning task

Página do item simplificado
dc.contributor.authorPinho, Nadine [UNIFESP]
dc.contributor.authorMoreira, Karin Monteiro [UNIFESP]
dc.contributor.authorHipólide, Débora Cristina [UNIFESP]
dc.contributor.authorSinigaglia-Coimbra, Rita [UNIFESP]
dc.contributor.authorFerreira, Tatiana Lima
dc.contributor.authorNobrega, Jose N.
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorMenezes Oliveira, Maria Gabriela [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Federal do ABC (UFABC)
dc.contributor.institutionCtr Addict & Mental Hlth
dc.date.accessioned2016-01-24T14:31:02Z
dc.date.available2016-01-24T14:31:02Z
dc.date.issued2013-01-01
dc.description.abstractWe investigated the relationship between deficits in fear memory induced by sleep deprivation and pCREB expression in the basal and central nuclei of the amygdala. Sleep deprivation reduced pCREB expression in the central nucleus compared to control or sleep recovered groups, and in the basal nucleus only compared to sleep recovered group. Moreover, 24 h of sleep recovery prior to training prevented changes in both pCREB expression and performance. (C) 2012 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psicobiol, BR-04024002 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Lab Fisiopatol Clin & Expt, Ctr Microscopia Eletron, BR-04024002 São Paulo, Brazil
dc.description.affiliationUniv Fed ABC, Math Computat & Cognit Ctr, Santo Andre, SP, Brazil
dc.description.affiliationCtr Addict & Mental Hlth, Res Imaging Ctr, Toronto, ON, Canada
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psicobiol, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Lab Fisiopatol Clin & Expt, Ctr Microscopia Eletron, BR-04024002 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipAFIP
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent221-224
dc.identifierhttp://dx.doi.org/10.1016/j.bbr.2012.08.043
dc.identifier.citationBehavioural Brain Research. Amsterdam: Elsevier B.V., v. 236, p. 221-224, 2013.
dc.identifier.doi10.1016/j.bbr.2012.08.043
dc.identifier.issn0166-4328
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35797
dc.identifier.wosWOS:000310929400028
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofBehavioural Brain Research
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectMemoryen
dc.subjectSleepen
dc.subjectCREBen
dc.subjectAmygdalaen
dc.subjectContextual fear conditioningen
dc.titleSleep deprivation alters phosphorylated CREB levels in the amygdala: Relationship with performance in a fear conditioning tasken
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos