What do Cochrane systematic reviews say about cardiac arrest management?

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dc.citation.issue2
dc.citation.volumev. 136
dc.contributor.authorPacheco, Rafael Leite
dc.contributor.authorTrevizo, Juliana [UNIFESP]
dc.contributor.authorSouza, Caio Augusto de [UNIFESP]
dc.contributor.authorAlves, Gabriel [UNIFESP]
dc.contributor.authorSakaya, Bruno [UNIFESP]
dc.contributor.authorThiago, Luciana [UNIFESP]
dc.contributor.authorGóis, Aécio Flávio Teixeira de [UNIFESP]
dc.contributor.authorRiera, Rachel [UNIFESP]
dc.coverageSao Paulo
dc.date.accessioned2020-07-20T16:31:17Z
dc.date.available2020-07-20T16:31:17Z
dc.date.issued2018
dc.description.abstractCONTEXT AND OBJECTIVE: Cardiac arrest is associated with high morbidity and mortality and imposes a significant burden on the healthcare system. Management of cardiac arrest patients is complex and involves approaches with multiple interventions. Here, we aimed to summarize the available evidence regarding the interventions used in cardiac arrest cases. DESIGN AND SETTING: Review of systematic reviews (SRs), conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo. METHODS: A systematic search was conducted to identify all Cochrane SRs that fulfilled the inclusion criteria. Titles and abstracts were screened by two authors. RESULTS: We included nine Cochrane SRs assessing compression techniques or devices (three SRs), defibrillation (two SRs) and other interventions (two SRs on hypothermia interventions, one on airway management and one on pharmacological intervention). The reviews included found qualities of evidence ranging from unknown to high, regarding the benefits of these interventions. CONCLUSION: This review included nine Cochrane systematic reviews that provided a diverse range of qualities of evidence (unknown to high) regarding interventions that are used in management of cardiac arrest. High-quality evidence was found by two systematic reviews as follows: (a) increased survival until hospital discharge with continuous compression, compared with interrupted chest compression, both administered by an untrained person and (b) no difference regarding the return of spontaneous circulation, comparing aminophylline and placebo, for bradyasystolic patients under cardiac arrest. Further studies are needed in order to reach solid conclusions.en
dc.description.affiliationUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Discipline Evidence Based Hlth, Sao Paulo, SP, Brazil
dc.description.affiliationCochrane Brazil, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Discipline Evidence Based Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Discipline Evidence Based Hlth, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent170-176
dc.identifierhttp://dx.doi.org/10.1590/1516-3180.2018.0083230318
dc.identifier.citationSao Paulo Medical Journal. Sao Paulo, v. 136, n. 2, p. 170-176, 2018.
dc.identifier.doi10.1590/1516-3180.2018.0083230318
dc.identifier.fileS1516-31802018000200170.pdf
dc.identifier.issn1516-3180
dc.identifier.scieloS1516-31802018000200170
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55848
dc.identifier.wosWOS:000432853900014
dc.language.isoeng
dc.publisherAssociacao Paulista Medicina
dc.relation.ispartofSao Paulo Medical Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectReview [publication type]en
dc.subjectHeart arresten
dc.subjectEvidence-based medicineen
dc.subjectEvidence-based practiceen
dc.titleWhat do Cochrane systematic reviews say about cardiac arrest management?en
dc.typeinfo:eu-repo/semantics/review
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