High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population

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dc.contributor.authorPassos-Castilho, Ana Maria [UNIFESP]
dc.contributor.authorReinaldo, Monica Renata [UNIFESP]
dc.contributor.authorde Sena, Anne [UNIFESP]
dc.contributor.authorGranato, Celso F. H. [UNIFESP]
dc.date.accessioned2019-08-19T11:48:28Z
dc.date.available2019-08-19T11:48:28Z
dc.date.issued2017
dc.description.abstractBrazil is a non-endemic country for hepatitis E virus (HEV) infection with seroprevalence from 1% to 4% in blood donors and the general population. However, data on seroprevalence of HEV in the country are still limited. This study evaluated the prevalence of past or present HEV infection in a group of blood donors representative of the general population of the city of Sao Paulo, Southeastern Brazil. Serum samples from 500 blood donors were tested from July to September 2014 by serological and molecular methods. Anti-HEV IgG antibodies were detected in 49 (9.8%) subjects and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Among the anti-HEV IgG positive subjects, only 1 had anti-HEV IgM while none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG than previously reported in the region. (C) 2017 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda.en
dc.description.affiliationUniv Fed São Paulo, Div Infect Dis, São Paulo, SP, Brazil
dc.description.affiliationFleury SA Grp, São Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed São Paulo, Div Infect Dis, São Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIDFAPESP: 2012/22925-3
dc.description.sponsorshipIDFAPESP: 2013/03701-0
dc.format.extent535-539
dc.identifierhttp://dx.doi.org/10.1016/j.bjid.2017.05.004
dc.identifier.citationBrazilian Journal Of Infectious Diseases. Rio De Janeiro, v. 21, n. 5, p. 535-539, 2017.
dc.identifier.doi10.1016/j.bjid.2017.05.004
dc.identifier.fileWOS000414276300008.pdf
dc.identifier.issn1413-8670
dc.identifier.scieloS1413-86702017000500535
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/51259
dc.identifier.wosWOS:000414276300008
dc.language.isoeng
dc.publisherElsevier Brazil
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHepatitis E virusen
dc.subjectBlood donorsen
dc.subjectSeroprevalenceen
dc.subjectBrazilen
dc.titleHigh prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general populationen
dc.typeinfo:eu-repo/semantics/article
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