Assessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humans

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dc.contributor.authorMaluf, E.
dc.contributor.authorBarros, HMT
dc.contributor.authorFrochtengarten, Mario Luiz [UNIFESP]
dc.contributor.authorBenti, R.
dc.contributor.authorLEITE, JR
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T11:40:05Z
dc.date.available2016-01-24T11:40:05Z
dc.date.issued1991-12-01
dc.description.abstractPassiflora species are used in folk medicine as hypnotic and sedative treatments. in this study the hypnotic-sedative effects and toxicity of Passiflora edulis were assessed in rats and mice and in healthy volunteers. It was verified that some samples of Passiflora edulis had a nonspecific central nervous system depressant effect. Furthermore, hepatobiliary and pancreatic toxicity to animals and humans were detected.en
dc.description.affiliationESCOLA PAULISTA MED SCH,DEPT PSYCHOBIOL,862 RUA BOTUCATU,BR-04023 São Paulo,BRAZIL
dc.description.affiliationUnifespESCOLA PAULISTA MED SCH,DEPT PSYCHOBIOL,862 RUA BOTUCATU,BR-04023 São Paulo,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent262-266
dc.identifierhttp://dx.doi.org/10.1002/ptr.2650050607
dc.identifier.citationPhytotherapy Research. W Sussex: John Wiley & Sons Ltd, v. 5, n. 6, p. 262-266, 1991.
dc.identifier.doi10.1002/ptr.2650050607
dc.identifier.issn0951-418X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/25232
dc.identifier.wosWOS:A1991GT67400006
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofPhytotherapy Research
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.subjectPASSIFLORA-EDULISen
dc.subjectSLEEPING-TIMEen
dc.subjectSEDATIVE HYPNOTIC EFFECTSen
dc.subjectTOXICITYen
dc.subjectDEPRESSANT EFFECTen
dc.titleAssessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humansen
dc.typeinfo:eu-repo/semantics/article
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