Malignant transformation of pleomorphic xanthoastrocytoma: case report

dc.contributor.authorTella Junior, Oswaldo Ignácio de [UNIFESP]
dc.contributor.authorHerculano, Marco Antonio
dc.contributor.authorPrandini, Mirto Nelso [UNIFESP]
dc.contributor.authorStávale, João Norberto [UNIFESP]
dc.contributor.authorAguiar, Paulo Henrique
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionJundiai Medicine School Neurosurgical Department
dc.contributor.institutionState University of São Paulo Neurosurgical Department
dc.date.accessioned2015-06-14T13:29:58Z
dc.date.available2015-06-14T13:29:58Z
dc.date.issued2003-03-01
dc.description.abstractWe report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.en
dc.description.abstractUm caso raro de transformação maligna de xantoastrocitoma pleomórfico é apresentado, discutido e ilustrado neste estudo. Descrevemos um caso de xantoastrocitoma pleomórfico diagnosticado como lesão isodensa no lobo fronto-temporal direito, em uma paciente de 26 anos. Na cirurgia, encontrou-se tumor mole, de cor amarelada, com cavidade cística. Cinco meses após o procedimento, a paciente foi submetida a nova intervenção que revelou um tumor friável, facilmente diferenciado do parênquima normal, com componentes císticos. O exame histopatológico demonstrou um xantoastrocitoma pleomórfico com transformação maligna. O tumor, no primeiro procedimento, era formado por astrócitos pleomórficos com células vacuolizadas e multinucleadas.pt
dc.description.affiliationFederal University of São Paulo Department of Neurosurgery
dc.description.affiliationFederal University of São Paulo Department of Pathology
dc.description.affiliationJundiai Medicine School Neurosurgical Department
dc.description.affiliationState University of São Paulo Neurosurgical Department
dc.description.affiliationUnifespUNIFESP, Department of Neurosurgery
dc.description.affiliationUnifespUNIFESP, Department of Pathology
dc.description.sourceSciELO
dc.format.extent104-106
dc.identifierhttp://dx.doi.org/10.1590/S0004-282X2003000100020
dc.identifier.citationArquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 61, n. 1, p. 104-106, 2003.
dc.identifier.doi10.1590/S0004-282X2003000100020
dc.identifier.fileS0004-282X2003000100020.pdf
dc.identifier.issn0004-282X
dc.identifier.scieloS0004-282X2003000100020
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/1676
dc.identifier.wosWOS:000182336700020
dc.language.isoeng
dc.publisherAcademia Brasileira de Neurologia - ABNEURO
dc.relation.ispartofArquivos de Neuro-Psiquiatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectxanthoastrocytomaen
dc.subjectastrocytomaen
dc.subjecttumoren
dc.subjecthistopathologyen
dc.subjectxantoastrocitomapt
dc.subjectastrocitomapt
dc.subjecttumorpt
dc.subjecthistopatologiapt
dc.titleMalignant transformation of pleomorphic xanthoastrocytoma: case reporten
dc.title.alternativeTransformação maligna de xantoastrocitoma pleomórfico: relato de casopt
dc.typeinfo:eu-repo/semantics/article
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