High rate of non-albicans candidemia in Brazilian tertiary care hospitals

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dc.contributor.authorColombo, Arnaldo Lopes [UNIFESP]
dc.contributor.authorNucci, Marcio [UNIFESP]
dc.contributor.authorSalomão, Reinaldo [UNIFESP]
dc.contributor.authorBranchini, MLM
dc.contributor.authorRichtmann, R.
dc.contributor.authorDerossi, A.
dc.contributor.authorWey, Sergio Barsanti [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)
dc.contributor.institutionHosp & Maternidade Santa Marcelina
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionHosp Servidor Publ Estadual
dc.contributor.institutionUniversidade do Estado do Rio de Janeiro (UERJ)
dc.date.accessioned2018-06-15T17:17:23Z
dc.date.available2018-06-15T17:17:23Z
dc.date.issued1999-08-01
dc.description.abstractIn order to evaluate the epidemiology of candidemia in Brazil, we performed a prospective multicenter study conducted in six general hospitals from Sao Paulo and Rio de Janeiro. We enrolled a total of 145 candidemic patients (85 males) with a median age of 32 years. Non-albicans species accounted for 63% of all episodes and the species most frequently causing candidemia were C. albicans (37%), C. parapsilosis (25%), C. tropicalis (24%), C. rugosa (5%), and C. glabrata (4%). Systemic azoles were used before the onset of candidemia in only six patients. There were no differences in the coexisting exposures or underlying diseases associated with the species most frequently causing candidemia. The overall crude mortality rate was 50%. Nosocomial candidemias in our tertiary hospitals are caused predominantly by non-albicans species, which are rarely fluconazole resistant. This predominance of non-albicans species could not be related to the previous use of azoles. (C) 1999 Elsevier Science Inc.en
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Dept Med,Div Infect Dis, Special Mycol Lab, BR-04023062 Sao Paulo, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Univ Hosp, Dept Internal Med, Div Hematol, Rio De Janeiro, Brazil
dc.description.affiliationHosp & Maternidade Santa Marcelina, Sao Paulo, Brazil
dc.description.affiliationUniv Estadual Campinas, Dept Med, Div Infect Dis, BR-13081970 Campinas, SP, Brazil
dc.description.affiliationHosp Servidor Publ Estadual, Sao Paulo, Brazil
dc.description.affiliationUniv Estado Rio de Janeiro, Univ Hosp, Rio De Janeiro, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Escola Paulista Med, Dept Med,Div Infect Dis, Special Mycol Lab, BR-04023062 Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent281-286
dc.identifierhttps://doi.org/10.1016/S0732-8893(99)00042-5
dc.identifier.citationDiagnostic Microbiology And Infectious Disease. New York: Elsevier Science Inc, v. 34, n. 4, p. 281-286, 1999.
dc.identifier.doi10.1016/S0732-8893(99)00042-5
dc.identifier.issn0732-8893
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/43486
dc.identifier.wosWOS:000081787200004
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofDiagnostic Microbiology And Infectious Disease
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.titleHigh rate of non-albicans candidemia in Brazilian tertiary care hospitalsen
dc.typeinfo:eu-repo/semantics/article
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