The Effectiveness of Treatments for Cocaine Dependence in Schizophrenic Patients: A Systematic Review

Página do item simplificado
dc.contributor.authorSabioni, Pamela [UNIFESP]
dc.contributor.authorRamos, Anna Carolina [UNIFESP]
dc.contributor.authorGalduróz, José Carlos Fernandes [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T17:05:14Z
dc.date.available2018-06-15T17:05:14Z
dc.date.issued2013-09-01
dc.description.abstractObjectives: To evaluate and compare the effectiveness of available treatments for cocaine dependence in schizophrenic patients.Method: We searched articles published between May 2002 and June 2012 in the following databases: Scopus, Pubmed and Web of Knowledge. The key words utilised were schizophrenia, dementia praecox, schizophrenic disorder, cocaine related disorder, cocaine abuse, cocaine addiction, cocaine dependence, treatment, therapeutic, and drug therapy.Selection of studies and data extraction: Original articles in English, Portuguese and Spanish were selected. Controlled, double-blind and open-label studies involving only human subjects were included in this review.Data Synthesis: We found studies on typical and atypical antipsychotics and one monoamine transporter antagonist. There were few indications of the effectiveness of atypical antipsychotic medications for the treatment of cocaine dependence in patients with schizophrenia.Conclusions: We suggest that further studies be conducted with atypical antipsychotic medicationsand greater methodological strictness, including using a placebo group in the studies, so that health professionals can determine the real effectiveness of this class of medication for the treatment of cocaine dependence in schizophrenic patients.en
dc.description.affiliationUniv Fed Sao Paulo, Dept Psychobiol, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Psychobiol, BR-04024002 Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent484-490
dc.identifierhttp://dx.doi.org/10.2174/1570159X11311050003
dc.identifier.citationCurrent Neuropharmacology. Sharjah: Bentham Science Publ Ltd, v. 11, n. 5, p. 484-490, 2013.
dc.identifier.doi10.2174/1570159X11311050003
dc.identifier.issn1570-159X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/43458
dc.identifier.wosWOS:000323764800003
dc.language.isoeng
dc.publisherBentham Science Publ Ltd
dc.relation.ispartofCurrent Neuropharmacology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectCocaineen
dc.subjectDependenceen
dc.subjectTreatmenten
dc.subjectSchizophreniaen
dc.titleThe Effectiveness of Treatments for Cocaine Dependence in Schizophrenic Patients: A Systematic Reviewen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Outras produções