COMPARISON BETWEEN CLEARANCE RATES of PLASMA KALLIKREIN and of PLASMA KALLIKREIN-ALPHA-MACROGLOBULIN COMPLEXES BY the LIVER

dc.contributor.authorOgata, H.
dc.contributor.authorKouyoumdjian, M.
dc.contributor.authorBorges, D. R.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T11:40:13Z
dc.date.available2016-01-24T11:40:13Z
dc.date.issued1993-07-01
dc.description.abstract1. Alpha-Macroglobulins (alphaMs) were isolated from the serum of injured rats through a two-stage method: gel filtration and ultracentrifugation.2. the clearance rates of rat plasma kallikrein (RPK) and alphaMs-RPK complexes were compared in an isolated rat liver perfusion system: the alphaMs-RPK complexes are cleared at a much slower rate (half-life ranging from 24 to > 120 min) than does RPK itself (half-life ranging from 13 to 18 min).en
dc.description.affiliationESCOLA PAULISTA MED,DEPT MED,DIV GASTROENTEROL,BR-04023 São Paulo,BRAZIL
dc.description.affiliationESCOLA PAULISTA MED,DEPT BIOCHEM,BR-04023 São Paulo,BRAZIL
dc.description.affiliationUnifespESCOLA PAULISTA MED,DEPT MED,DIV GASTROENTEROL,BR-04023 São Paulo,BRAZIL
dc.description.affiliationUnifespESCOLA PAULISTA MED,DEPT BIOCHEM,BR-04023 São Paulo,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent1047-1051
dc.identifierhttp://dx.doi.org/10.1016/0020-711X(93)90120-4
dc.identifier.citationInternational Journal of Biochemistry. Oxford: Pergamon-Elsevier B.V., v. 25, n. 7, p. 1047-1051, 1993.
dc.identifier.doi10.1016/0020-711X(93)90120-4
dc.identifier.issn0020-711X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/25339
dc.identifier.wosWOS:A1993LK67800013
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofInternational Journal of Biochemistry
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.titleCOMPARISON BETWEEN CLEARANCE RATES of PLASMA KALLIKREIN and of PLASMA KALLIKREIN-ALPHA-MACROGLOBULIN COMPLEXES BY the LIVERen
dc.typeinfo:eu-repo/semantics/article
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