COMPARISON BETWEEN CLEARANCE RATES of PLASMA KALLIKREIN and of PLASMA KALLIKREIN-ALPHA-MACROGLOBULIN COMPLEXES BY the LIVER
dc.contributor.author | Ogata, H. | |
dc.contributor.author | Kouyoumdjian, M. | |
dc.contributor.author | Borges, D. R. | |
dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | |
dc.date.accessioned | 2016-01-24T11:40:13Z | |
dc.date.available | 2016-01-24T11:40:13Z | |
dc.date.issued | 1993-07-01 | |
dc.description.abstract | 1. Alpha-Macroglobulins (alphaMs) were isolated from the serum of injured rats through a two-stage method: gel filtration and ultracentrifugation.2. the clearance rates of rat plasma kallikrein (RPK) and alphaMs-RPK complexes were compared in an isolated rat liver perfusion system: the alphaMs-RPK complexes are cleared at a much slower rate (half-life ranging from 24 to > 120 min) than does RPK itself (half-life ranging from 13 to 18 min). | en |
dc.description.affiliation | ESCOLA PAULISTA MED,DEPT MED,DIV GASTROENTEROL,BR-04023 São Paulo,BRAZIL | |
dc.description.affiliation | ESCOLA PAULISTA MED,DEPT BIOCHEM,BR-04023 São Paulo,BRAZIL | |
dc.description.affiliationUnifesp | ESCOLA PAULISTA MED,DEPT MED,DIV GASTROENTEROL,BR-04023 São Paulo,BRAZIL | |
dc.description.affiliationUnifesp | ESCOLA PAULISTA MED,DEPT BIOCHEM,BR-04023 São Paulo,BRAZIL | |
dc.description.source | Web of Science | |
dc.format.extent | 1047-1051 | |
dc.identifier | http://dx.doi.org/10.1016/0020-711X(93)90120-4 | |
dc.identifier.citation | International Journal of Biochemistry. Oxford: Pergamon-Elsevier B.V., v. 25, n. 7, p. 1047-1051, 1993. | |
dc.identifier.doi | 10.1016/0020-711X(93)90120-4 | |
dc.identifier.issn | 0020-711X | |
dc.identifier.uri | http://repositorio.unifesp.br/handle/11600/25339 | |
dc.identifier.wos | WOS:A1993LK67800013 | |
dc.language.iso | eng | |
dc.publisher | Elsevier B.V. | |
dc.relation.ispartof | International Journal of Biochemistry | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.license | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
dc.title | COMPARISON BETWEEN CLEARANCE RATES of PLASMA KALLIKREIN and of PLASMA KALLIKREIN-ALPHA-MACROGLOBULIN COMPLEXES BY the LIVER | en |
dc.type | info:eu-repo/semantics/article |