High-resolution Manometry Findings in Patients After Sclerotherapy for Esophageal Varices

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dc.citation.issue2
dc.citation.volume22
dc.contributor.authorHerbella, Fernando Augusto Mardiros [UNIFESP]
dc.contributor.authorColleoni, Ramiro [UNIFESP]
dc.contributor.authorBot, Luiz [UNIFESP]
dc.contributor.authorVicentine, Fernando Pompeu Piza [UNIFESP]
dc.contributor.authorPatti, Marco G.
dc.coverageGangnam-Gu
dc.date.accessioned2020-07-22T13:23:16Z
dc.date.available2020-07-22T13:23:16Z
dc.date.issued2016
dc.description.abstractBackground/Aims Endoscopic therapy for esophageal varices may lead to esophageal dysmotility. High-resolution manometry is probably the more adequate tool to measure esophageal motility in these patients. This study aimed to evaluate esophageal motility using high resolution manometry following eradication of esophageal varices by endoscopic sclerotherapy. Methods We studied 21 patients (11 women, age 52 [45-59] years). All patients underwent eradication of esophageal varices with endoscopic sclerotherapy and subsequent high resolution manometry. Results A significant percentage of defective lower esophageal sphincter (basal pressure 14.3 [8.0-20.0] mmHgen
dc.description.abstract43% hypertonic) and hypocontractility (distal esophageal amplitude 50 [31-64] mmHgen
dc.description.abstractproximal esophageal amplitude 40 [31-61] mmHgen
dc.description.abstractdistal contractile integral 617 [403-920] mmHg center dot sec center dot cmen
dc.description.abstract48% ineffective) was noticed. Lower sphincter basal pressure and esophageal amplitude correlated inversely with the number of sessions (P < 0.001). No manometric parameter correlated with symptoms or interval between last endoscopy and manometry. Conclusions Esophageal motility after endoscopic sclerotherapy is characterized by: (1) defective lower sphincter and (2) defective and hypotensive peristalsis. Esophageal dysmotility is associated to an increased number of endoscopic sessions, but manometric parameters do not predict symptoms.en
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Dept Surg, Sao Paulo, Brazil
dc.description.affiliationUniv Chicago, Dept Surg, 5841 S Maryland Ave, Chicago, IL 60637 USA
dc.description.affiliationUnifespUniv Fed Sao Paulo, Escola Paulista Med, Dept Surg, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent226-230
dc.identifierhttp://dx.doi.org/10.5056/jnm15132
dc.identifier.citationJournal Of Neurogastroenterology And Motility. Gangnam-Gu, v. 22, n. 2, p. 226-230, 2016.
dc.identifier.doi10.5056/jnm15132
dc.identifier.fileWOS000373662200008.pdf
dc.identifier.issn2093-0879
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/56129
dc.identifier.wosWOS:000373662200008
dc.language.isoeng
dc.publisherKorean Soc Neurogastroenterology & Motility
dc.relation.ispartofJournal Of Neurogastroenterology And Motility
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEsophageal motility disordersen
dc.subjectEsophageal varicesen
dc.subjectHypertension, portalen
dc.subjectManometryen
dc.subjectSclerotherapyen
dc.titleHigh-resolution Manometry Findings in Patients After Sclerotherapy for Esophageal Varicesen
dc.typeinfo:eu-repo/semantics/article
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