Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

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dc.citation.issue3
dc.citation.volume58
dc.contributor.authorMiller, Andrew R.
dc.contributor.authorRoisman, Luiz [UNIFESP]
dc.contributor.authorZhang, Qinqin
dc.contributor.authorZheng, Fang
dc.contributor.authorDias, Joao Rafael de Oliveira
dc.contributor.authorYehoshua, Zohar
dc.contributor.authorSchaal, Karen B.
dc.contributor.authorFeuer, William
dc.contributor.authorGregori, Giovanni
dc.contributor.authorChu, Zhongdi
dc.contributor.authorChen, Chieh-Li
dc.contributor.authorKubach, Sophie
dc.contributor.authorAn, Lin
dc.contributor.authorStetson, Paul F.
dc.contributor.authorDurbin, Mary K.
dc.contributor.authorWang, Ruikang K.
dc.contributor.authorRosenfeld, Philip J.
dc.coverageRockville
dc.date.accessioned2020-07-17T14:02:46Z
dc.date.available2020-07-17T14:02:46Z
dc.date.issued2017
dc.description.abstractPURPOSE. The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). METHODS. Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 x 3-and 6 x 6-mm(2) scans were obtained on both instruments. The 3 x 3-mm(2) SS-OCTA scans consisted of 300 A-scans per B-scan at 300 B-scan positions, and the SD-OCTA scans consisted of 245 A-scans at 245 B-scan positions. The 6 x 6-mm(2) SS-OCTA scans consisted of 420 A-scans per B-scan at 420 B-scan positions, and the SD-OCTA scans consisted of 350 A-scans and 350 B-scan positions. B-scans were repeated four times at each position in the 3 x 3-mm(2) scans and twice in the 6 x 6-mm(2) scans. Choroidal neovascularization was excluded if not fully contained within the 3 x 3-mm(2) scans. The same algorithm was used to detect CNV on both instruments. Two graders outlined the CNV, and the lesion areas were compared between instruments. RESULTS. Twenty-seven consecutive eyes from 23 patients were analyzed. For the 3 x 3-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.17 and 1.01 mm(2), respectively (P = 0.047). For the 6 x 6-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.24 and 0.74 mm(2) (P = 0.003). CONCLUSIONS. The areas of CNV tended to be larger when imaged with SS-OCTA than with SD-OCTA, and this difference was greater for the 6 x 6-mm(2) scans.en
dc.description.affiliationUniv Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USA
dc.description.affiliationUniv Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil
dc.description.affiliationUniv Washington, Dept Bioengn, Seattle, WA 98195 USA
dc.description.affiliationCarl Zeiss Meditec Inc, Adv Dev, Dublin, CA USA
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCarl Zeiss Meditec, Inc.
dc.description.sponsorshipNational Eye Institute
dc.description.sponsorshipResearch to Prevent Blindness, Inc. (New York, NY)
dc.description.sponsorshipNational Eye Institute Center Core Grant
dc.description.sponsorshipCAPES Foundation, Ministry of Education of Brazil (Brasilia, Brazil)
dc.description.sponsorshipGerman Research Foundation
dc.description.sponsorshipIDNational Eye Institute: R01EY024158
dc.description.sponsorshipIDNational Eye Institute Center Core Grant: P30EY014801
dc.description.sponsorshipIDGerman Research Foundation: SCHA 1869/1-1
dc.format.extent1499-1505
dc.identifierhttp://dx.doi.org/10.1167/iovs.16-20969
dc.identifier.citationInvestigative Ophthalmology & Visual Science. Rockville, v. 58, n. 3, p. 1499-1505, 2017.
dc.identifier.doi10.1167/iovs.16-20969
dc.identifier.fileWOS000398089000018.pdf
dc.identifier.issn0146-0404
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55011
dc.identifier.wosWOS:000398089000018
dc.language.isoeng
dc.publisherAssoc Research Vision Ophthalmology Inc
dc.relation.ispartofInvestigative Ophthalmology & Visual Science
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectoptical coherence tomography angiographyen
dc.subjectOCTAen
dc.subjectswept-source OCTAen
dc.subjectspectral-domain OCTAen
dc.subjectneovascular AMDen
dc.subjectchoroidal neovascularizationen
dc.titleComparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularizationen
dc.typeinfo:eu-repo/semantics/article
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