Neuromuscular electrical stimulation improves exercise tolerance in patients with advanced heart failure on continuous intravenous inotropic support userandomized controlled trial

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dc.citation.issue1
dc.citation.volume32
dc.contributor.authorForestieri, Patricia [UNIFESP]
dc.contributor.authorBolzan, Douglas Willian [UNIFESP]
dc.contributor.authorSantos, Vinicius Batista [UNIFESP]
dc.contributor.authorMoreira, Rita Simone Lopes [UNIFESP]
dc.contributor.authorAlmeida, Dirceu Rodrigues de [UNIFESP]
dc.contributor.authorTrimer, Renata
dc.contributor.authorBrito, Flavio de Souza [UNIFESP]
dc.contributor.authorBorghi-Silva, Audrey
dc.contributor.authorCarvalho, Antonio Carlos de Camargo [UNIFESP]
dc.contributor.authorArena, Ross
dc.contributor.authorGomes, Walter José [UNIFESP]
dc.contributor.authorGuizilini, Solange [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.coverageLondon
dc.date.accessioned2020-07-02T18:52:14Z
dc.date.available2020-07-02T18:52:14Z
dc.date.issued2018
dc.description.abstractObjective: To evaluate the impact of a short-term neuromuscular electrical stimulation program on exercise tolerance in hospitalized patients with advanced heart failure who have suffered an acute decompensation and are under continuous intravenous inotropic support. Design: A randomized controlled study. Subjects: Initially, 195 patients hospitalized for decompensated heart failure were recruited, but 70 were randomized. Intervention: Patients were randomized into two groups: control group subject to the usual care (n = 35); neuromuscular electrical stimulation group (n = 35) received daily training sessions to both lower extremities for around two weeks. Main measures: The baseline 6-minute walk test to determine functional capacity was performed 24 hours after hospital admission, and intravenous inotropic support dose was daily checked in all patients. The outcomes were measured in two weeks or at the discharge if the patients were sent back home earlier than two weeks. Results: After losses of follow-up, a total of 49 patients were included and considered for final analysis (control group, n = 25 and neuromuscular electrical stimulation group, n = 24). The neuromuscular electrical stimulation group presented with a higher 6-minute walk test distance compared to the control group after the study protocol (293 ± 34.78 m vs. 265.8 ± 48.53 m, P < 0.001, respectively). Neuromuscular electrical stimulation group also demonstrated a significantly higher dose reduction of dobutamine compared to control group after the study protocol (2.72 ± 1.72 µg/kg/min vs. 3.86 ± 1.61 µg/kg/min, P = 0.001, respectively). Conclusion: A short-term inpatient neuromuscular electrical stimulation rehabilitation protocol improved exercise tolerance and reduced intravenous inotropic support necessity in patients with advanced heart failure suffering a decompensation episode.en
dc.description.affiliationUniv Fed Sao Paulo, Sao Paulo Hosp, Cardiol & Cardiovasc Surg Discipline, Rua Napoleao de Barros,715,3 Andar, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Carlos, Cardiopulm Physiotherapy Lab, Sao Carlos, Brazil
dc.description.affiliationUniv Illinois, Coll Appl Hlth Sci, Dept Phys Therapy, Chicago, IL USA
dc.description.affiliationUniv Fed Sao Paulo, Physiotherapy Sch, Dept Human Mot Sci, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Sao Paulo Hosp, Cardiol & Cardiovasc Surg Discipline, Rua Napoleao de Barros,715,3 Andar, BR-04024002 Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent66-74
dc.identifierhttps://dx.doi.org/10.1177/0269215517715762
dc.identifier.citationClinical Rehabilitation. London, v. 32, n. 1, p. 66-74, 2018.
dc.identifier.doi10.1177/0269215517715762
dc.identifier.fileWOS000418381700008.pdf
dc.identifier.issn0269-2155
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53963
dc.identifier.wosWOS:000418381700008
dc.language.isoeng
dc.publisherSage Publications Ltd
dc.relation.ispartofClinical Rehabilitation
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCardiac rehabilitationen
dc.subjectFunctional capacityen
dc.subjectNeuromuscular stimulationen
dc.subjectHeart failureen
dc.titleNeuromuscular electrical stimulation improves exercise tolerance in patients with advanced heart failure on continuous intravenous inotropic support userandomized controlled trialen
dc.typeinfo:eu-repo/semantics/article
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