Amniotic fluid "sludge" is an independent risk factor for preterm delivery
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Date
2016
Authors
Hatanaka, Alan Roberto [UNIFESP]
Mattar, Rosiane [UNIFESP]
Nishimoto Kawanami, Tatiana Emy [UNIFESP]
Franca, Marcelo Santucci [UNIFESP]
Rolo, Liliam Cristine [UNIFESP]
Yamamoto Nomura, Roseli Mieko [UNIFESP]
Araujo Junior, Edward [UNIFESP]
Machado Nardozza, Luciano Marcondes [UNIFESP]
Moron, Antonio Fernandes [UNIFESP]
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Abstract
Objective: To determine the prevalence and the clinical significance of amniotic fluid sludge (AFS) in asymptomatic patients at low and high risk for spontaneous preterm delivery.Method: A prospective cohort study was conducted on 195 singleton pregnancies at low or high risk for preterm birth (PTB) between the 16th and 26th weeks. Cervical length (CL) <25mm and the presence of AFS were evaluated. The risk for preterm delivery before 28, 32, 35 and 37 weeks were determined according to the presence of AFS, CL<25mm and history of high risk for PTB. Stepwise logistic regression was performed to compare variables.Results: AFS was an independent risk factor for PTB<35 weeks (OR: 3.08, 95% CI: 1.13-8.34, p=0.027) but not for PTB<28, 32 and 37 weeks. CL<25mm was an independent risk factor for PTB<28, 32 and 35 but not for PTB<37 weeks. High risk for PTB was not found as an independent risk factor for PTB.Conclusion: AFS is an independent risk factor for PTB before 35 weeks.
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Journal Of Maternal-Fetal & Neonatal Medicine. Abingdon, v. 29, n. 1, p. 120-125, 2016.