Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the management of oral squamous carcinoma

Brentani, Ricardo Renzo [UNIFESP]; Kowalski, Luiz Paulo [UNIFESP]; Soares, Jose F.; Torloni, Humberto; Pereira, Raimunda N.; Ikeda, Mauro Kasuo [UNIFESP]; Andrade, Roberto Paulo de [UNIFESP]; Magrin, Jose [UNIFESP]; Miguel, Roberto EV; Santos, Carlos R.; Saba, Leda MB; Salvajoli, João Victor [UNIFESP]; Curado, Maria P.; Oliveira, Jose C.; Montandon, Paula O.; Machado, Marcio M.; Denofrio, Giovana F.; Quinta, Waldir C.; Alvarez, Rene B.; Alencar, Rita CG; Ferraz, Alberto R.; Brandao, Lenine Garcia; Cernea, Claudio Roberto; Santos, Luiz RM; Araujo, Virgilius; Antonangelo, Avelino; Silva, João LF; Della-Molle, Romuado; Feriancic, Carlos V.; Oliveira, Benedito V.; Ramos, Gil; Antunes, Lysandro S.; Andrade Sobrinho, Jose A.; Rapoport, Abrão [UNIFESP]; Carvalho, Marcos B.; Fava, Antonio S.; Gois Filho, Jose Francisco de [UNIFESP]; Chagas, José Francisco de Sales [UNIFESP]; Kanda, Jossi Ledo [UNIFESP]; Gripp, Flavio M.; Ribas, Marcelo H.; Castro, Ivan S.; Oliveira, Joni MS; Oliveira, José AM; Carvalho, Ricardo C.; Araujo, Lacerda B.; Pontes, Paulo AL [UNIFESP]; Gregorio, Luiz C. [UNIFESP]; Abrahão, Marcio [UNIFESP]; Cervantes, Onivaldo [UNIFESP]; Paiva, Marcos Bandiera [UNIFESP]; Hebbel, Werner S. [UNIFESP]; Fujita, Reginaldo Raimundo [UNIFESP]; Motta, Pedro HH [UNIFESP]; Segreto, Roberto Araujo [UNIFESP]; Herter, Nilton T.; Mota, Neiro W.; Scholl, Joao G.; Kroef, Ricardo G.; Godoy, Paulo RF; Brazilian Head Neck Canc Study Grp

Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the management of oral squamous carcinoma

Date

1998-11-01

Authors

Brentani, Ricardo Renzo [UNIFESP]

Kowalski, Luiz Paulo [UNIFESP]

Soares, Jose F.

Torloni, Humberto

Pereira, Raimunda N.

Ikeda, Mauro Kasuo [UNIFESP]

Andrade, Roberto Paulo de [UNIFESP]

Magrin, Jose [UNIFESP]

Miguel, Roberto EV

Santos, Carlos R.

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Artigo

Abstract

BACKGROUND: Elective treatment of the neck in oral squamous cell carcinoma has changed over the last 20 years. The main object of this report is to present the results of a multi-institutional prospective study designed to compare standard treatment with modified radical classical neck dissection (MRND) to supraomohyoid neck dissection (SOH) in the management of the clinically negative neck in oral cancer patients.PATIENTS AND METHODS: A total of 148 patients were included in the trial. All patients had previously untreated T2 to T4 NO squamous cell carcinoma of the oral tongue (62 cases), floor of the mouth (49 cases), inferior gingiva (12 cases), or retromolar trigone (25 cases). Tumor stages were T2, 91; T3, 27; and T4, 30. There were no significant imbalances between groups.RESULTS: The false-negative rate was 23%, and most positive nodes were sited at level II and III. Complications were seen in 41% of MRND patients and in 25% of SOH patients (P = 0.043). Median total duration of hospitalization was 9 days in MRND patients and 7 days in the SOH group. To date, 19 and 16 patients presented with local and neck recurrences, respectively. The 60-month actuarial survival rates were 63% in the MRND group and 67% in the SOH group (P = 0.7150).CONCLUSIONS: This study demonstrates that the recurrence and survival rates were similar in both groups. SOH neck dissection can be recommended as standard elective treatment for patients with T2-T4 oral squamous cell carcinomas. Am J Surg. 1998;176:422-427. (C) 1998 by Excerpta Medica, Inc.

Citation

American Journal Of Surgery. New York: Cahners Publ Co, v. 176, n. 5, p. 422-427, 1998.

URI

http://repositorio.unifesp.br/handle/11600/42399

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EPM - Artigos

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