T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals

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Date
2007-04-01Author
Iwai, Leo Kei
Yoshida, Marcia
Sadahiro, Aya
Silva, Washington Robert da
Marin, Maria Lucia
Goldberg, Anna Carla
Juliano, Maria Aparecida
Juliano, Luiz
Shikanai-Yasuda, Maria Aparecida
Kalil, Jorge
Cunha-Neto, Edecio
Travassos, Luiz R. [UNIFESP]
Type
ArtigoISSN
1556-6811Is part of
Clinical and Vaccine ImmunologyDOI
10.1128/CVI.00458-06Metadata
Show full item recordAbstract
Vaccines with synthetic peptides induce the immune response to epitopes that bind to several RLA alleles. By using a TEPITOPE algorithm, we selected and analyzed the T-cell responses of peripheral blood mononuclear cells from 29 paracoccidioidomycosis (PCM) patients to peptides of the immunodominant gp43 antigen of Paracoccidioides brasiliensis, the causative agent of PCM.
Citation
Clinical and Vaccine Immunology. Washington: Amer Soc Microbiology, v. 14, n. 4, p. 474-476, 2007.Collections
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