Antifungal drug susceptibility profile of Pichia anomala isolates from patients presenting with nosocomial fungemia
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2007-04-01
Autores
Ribeiro da Matta, Vania Lucia
Melhem, Marcia de Souza Carvalho
Colombo, Arnaldo Lopes [UNIFESP]
Moretti, Maria Luiza
Rodero, Laura
Duboc de Almeida, Gisele Madeira
Martins, Marilena dos Anjos
Costa, Silvia Figueiredo
Dias, Maria Beatriz G. Souza
Nucci, Marcio
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In vitro susceptibility of 58 isolates of Pichia anomala to five antifungal drugs using two broth microdilution methods (CLSI and EUCAST) was analyzed. Low susceptibility to itraconazole was observed. Fluconazole, voriconazole, amphotericin B, and caspofungin showed good antifungal activity, although relatively high drug concentrations were necessary to inhibit the isolates.
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Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 51, n. 4, p. 1573-1576, 2007.