Successful birth after intrafallopian transfer of microhatched embryos
Castellotti, Daniella Spilborghs
Motta, Eduardo Leme Alves da [UNIFESP]
Alegretti, José Roberto
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Objective: To present a successful transfer of microhatched embryos to the fallopian tubes via microlaparoscopy.Design: Case report.Setting: Private practice affiliated with a medical university.Patient: A 40-year-old woman with primary infertility, mildly elevated baseline FSH levels, and a history of poor ovarian response to ovulation induction. Her husband had severe oligoospermia after vasectomy reversal.Intervention(s): Late luteal leuprolide acetate to pituitary down-regulation followed by pure FSH, 300 IU, and hMG, 300 IU, daily for ovulation induction. Transvaginal oocyte retrieval, intracytoplasmic sperm injection, assisted embryo hatching, microlaparoscopic intrafallopian ET.Main Outcome Measure(s): Amniocentesis at the 14th week of gestation revealed a normal karyotype (46,XX); birth of a normal female infant (3700 g).Result(s): Establishment of a single, viable intrauterine gestation followed by a vaginal delivery at term.Conclusion(s): This case shows the possibility of using assisted-hatched embryos for laparoscopic intrafallopian tube transfer. (C) 1997 by American Society for Reproductive Medicine.
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