Estudo da transmissao materno fetal do virus linfotropico de celulas T humanas do tipo II em um grupo indigena kaiapo
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Data
1999
Autores
Novoa, Patricia Correia Rodrigues [UNIFESP]
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Dissertação de mestrado
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Resumo
HTLV-11 infection has been shown to be endemic in a number of indigenous populations in North, Central, and South America. Previous studies on small numbers of Guaymi lndians, in Changuinola, Panama, have indicated there might also be groups with endemic infection in that country. Several of the southern American Indian populations have documented a high seroprevalence rates suggesting that there are foci of endemic infection in the Amazon region.The existence of infection with Human T Lymphotropic Virus Type II has been recently demonstrated among the Kaiapo indians. The modes of transmission of HTLV-1 and II are generally similar to those of Human Immunodeficiency Virus (HIV) and include mother-to-child transmission by blood transfusion and among intravenous drug users and sexual intercourse. in the present study, we have employed serological and molecular methods to estimate the rate of mother-to-child transmission of HTLV-II in Kaiapo Indians from Xingu Nacional Park in the northern region of Brazil. Sera (238) from two lndian groups were collected in January 1996 and analyzed by ELISA and Western Blot. One hundred and nine samples were reactive by both technics, showing a seroprevalence rate of 45,7 por cento. Of these, twenty nine samples were from mothers and fifty three from their children. Among children with ages between 18 months and 12 years, 47,5 por cento Vertical transmission is an important route of infection. HTLV-11 has alredy been detected in breast milk of infected mothers and there has been one reported case where transmission of HTLV-11 appears to have directly resulted from breast feeding
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Citação
São Paulo: [s.n.], 1999. 97 p. ilustab.